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pubmed-article:7955198pubmed:abstractTextThe study objective was to determine whether Hirulog, a direct thrombin inhibitor, has potential efficacy and safety in the prevention of deep vein thrombosis (DVT) in orthopedic patients. A phase 2 open-label, dose-escalating design was used to study 222 unselected patients undergoing major hip or knee surgery in tertiary-care, university-affiliated hospitals.lld:pubmed
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pubmed-article:7955198pubmed:articleTitleUse of Hirulog in the prevention of venous thrombosis after major hip or knee surgery.lld:pubmed
pubmed-article:7955198pubmed:affiliationDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.lld:pubmed
pubmed-article:7955198pubmed:publicationTypeJournal Articlelld:pubmed
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