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pubmed-article:7944352pubmed:abstractTextFive enzyme inhibitors (phenylmethylsulfonyl fluoride, 4-amidinophenylmethanesulfonyl fluoride, 4-(2-aminoethyl)benzenesulfonyl fluoride, N alpha-p-tosyl-L-lysine chloromethyl ketone, and N-tosyl-L-phenylalanine chloromethyl ketone) in buffer, DMSO, or stock solutions were completely degraded by adding 1M NaOH and the final reaction mixtures were not mutagenic. The stability of these compounds decreased as the pH increased.lld:pubmed
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pubmed-article:7944352pubmed:articleTitleDegradation and disposal of some enzyme inhibitors. Scientific note.lld:pubmed
pubmed-article:7944352pubmed:affiliationProgram Resources, Inc./DynCorp, Environmental Control and Research Program, NCI-Frederick Cancer Research and Development Center, MD 21702-1201.lld:pubmed
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