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pubmed-article:7918053pubmed:abstractTextAn adaptation of the standard fluorescence in situ hybridization (FISH) technique allowing rapid analysis (4 h) has been used to study the prevalence of trisomy 12 in 33 patients with B-CLL, of whom 54% have been shown to have this abnormality. The presence of trisomy 12 has been compared with clinical parameters, and there may be a relationship between the prevalence of trisomy 12 in B-CLL and duration of disease.lld:pubmed
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pubmed-article:7918053pubmed:authorpubmed-author:LeylandM JMJlld:pubmed
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pubmed-article:7918053pubmed:dateRevised2007-11-15lld:pubmed
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pubmed-article:7918053pubmed:articleTitleTrisomy 12 in B-cell chronic lymphocytic leukaemia: an evaluation of 33 patients by direct fluorescence in situ hybridization (FISH).lld:pubmed
pubmed-article:7918053pubmed:affiliationDepartment of Haematology, East Birmingham Hospital.lld:pubmed
pubmed-article:7918053pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:7918053pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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