pubmed-article:791447 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:791447 | lifeskim:mentions | umls-concept:C0006142 | lld:lifeskim |
pubmed-article:791447 | lifeskim:mentions | umls-concept:C0085957 | lld:lifeskim |
pubmed-article:791447 | lifeskim:mentions | umls-concept:C0544452 | lld:lifeskim |
pubmed-article:791447 | lifeskim:mentions | umls-concept:C0038952 | lld:lifeskim |
pubmed-article:791447 | lifeskim:mentions | umls-concept:C0205179 | lld:lifeskim |
pubmed-article:791447 | pubmed:issue | 6046 | lld:pubmed |
pubmed-article:791447 | pubmed:dateCreated | 1977-1-29 | lld:pubmed |
pubmed-article:791447 | pubmed:abstractText | Forty-five patients with disseminated breast cancer were given a trial of combination chemotherapy consisting of fluorouracil, adriamycin, and cyclophosphamide (FAC) and immunotherapy with BCG given by scarification. The results were compared with those in a comparable group of 44 patients treated with FAC alone immediately before the chemoimmunotherapy study. The remission rates (73% and 76% for FAC and FAC-BCG respectively) were similar in both studies. The durations of remission for patients on FAC-BCG (medium 12 months) were longer than remissions achieved for patients given FAC alone (median 8 months) (P = 0.068). The most notable effect of BCG was on survival. Thus 21 out of 34 patients achieving remission on FAC-BCG were alive at the time of the last follow-up examination (median over 22 months) compared with 11 out of 32 patients achieving remission on FAC (median 15 months) (P = 0.01). Twenty-six of the 45 patients given FAC-BCG were alive at the time of the last follow-up examination (median over 22 months) compared with 12 of the 44 patients given FAC (median 15 months) (P = 0.005). Although the apparent benefit of BCG could be explained by a maldistribution of some prognostic factors, the data suggest that further trial of chemoimmunotherapy of breast cancer should be carried out. | lld:pubmed |
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pubmed-article:791447 | pubmed:language | eng | lld:pubmed |
pubmed-article:791447 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:791447 | pubmed:citationSubset | AIM | lld:pubmed |
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pubmed-article:791447 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:791447 | pubmed:month | Nov | lld:pubmed |
pubmed-article:791447 | pubmed:issn | 0007-1447 | lld:pubmed |
pubmed-article:791447 | pubmed:author | pubmed-author:HershE MEM | lld:pubmed |
pubmed-article:791447 | pubmed:author | pubmed-author:FreireichE... | lld:pubmed |
pubmed-article:791447 | pubmed:author | pubmed-author:GottliebJ AJA | lld:pubmed |
pubmed-article:791447 | pubmed:author | pubmed-author:BurgessM AMA | lld:pubmed |
pubmed-article:791447 | pubmed:author | pubmed-author:LivingstonR... | lld:pubmed |
pubmed-article:791447 | pubmed:author | pubmed-author:GuttermanJ... | lld:pubmed |
pubmed-article:791447 | pubmed:author | pubmed-author:MavligitG MGM | lld:pubmed |
pubmed-article:791447 | pubmed:author | pubmed-author:BlumenscheinG... | lld:pubmed |
pubmed-article:791447 | pubmed:author | pubmed-author:HortobagyiGG | lld:pubmed |
pubmed-article:791447 | pubmed:author | pubmed-author:CardenasJ OJO | lld:pubmed |
pubmed-article:791447 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:791447 | pubmed:day | 20 | lld:pubmed |
pubmed-article:791447 | pubmed:volume | 2 | lld:pubmed |
pubmed-article:791447 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:791447 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:791447 | pubmed:pagination | 1222-5 | lld:pubmed |
pubmed-article:791447 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:791447 | pubmed:year | 1976 | lld:pubmed |
pubmed-article:791447 | pubmed:articleTitle | Chemoimmunotherapy of advanced breast cancer: prolongation of remission and survival with BCG. | lld:pubmed |
pubmed-article:791447 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:791447 | pubmed:publicationType | Clinical Trial | lld:pubmed |
pubmed-article:791447 | pubmed:publicationType | Controlled Clinical Trial | lld:pubmed |
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