pubmed-article:7906328 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7906328 | lifeskim:mentions | umls-concept:C0024530 | lld:lifeskim |
pubmed-article:7906328 | lifeskim:mentions | umls-concept:C0011900 | lld:lifeskim |
pubmed-article:7906328 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
pubmed-article:7906328 | lifeskim:mentions | umls-concept:C1510438 | lld:lifeskim |
pubmed-article:7906328 | lifeskim:mentions | umls-concept:C1553114 | lld:lifeskim |
pubmed-article:7906328 | lifeskim:mentions | umls-concept:C0439831 | lld:lifeskim |
pubmed-article:7906328 | lifeskim:mentions | umls-concept:C1741222 | lld:lifeskim |
pubmed-article:7906328 | lifeskim:mentions | umls-concept:C0441090 | lld:lifeskim |
pubmed-article:7906328 | pubmed:issue | 8897 | lld:pubmed |
pubmed-article:7906328 | pubmed:dateCreated | 1994-3-22 | lld:pubmed |
pubmed-article:7906328 | pubmed:abstractText | Two field studies in Kenya and an experimental challenge study in the USA were done to assess the accuracy of a dipstick antigen-capture assay based on qualitative detection of Plasmodium falciparum histidine-rich protein 2 (PfHRP-2) in peripheral blood for diagnosis of P falciparum infection. In these studies, the assay was 96.5-100% sensitive for detection of greater than 60 P falciparum asexual parasites/microL blood, 70-81% sensitive for 11-60 parasites/microL blood, and 11-67% sensitive for 10 parasites or less/microL blood. Specificity was 95% (95% CI 85-105%; n = 20) among naive American volunteers, 98% (96-101%; n = 112) among volunteers exposed to the bite of P falciparum-infected mosquitoes, and 88% (84-92%; n = 285) among Kenyans living in an area with holoendemic malaria. Our results also indicated that PfHRP-2 antigen was not detectable in blood 6 days after initiation of curative chemotherapy, and suggest that such circulating antigens rarely lead to false-positive tests. The dipstick assay's sensitivity, specificity, simplicity, and speed may make it an important tool in the battle against malaria. | lld:pubmed |
pubmed-article:7906328 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7906328 | pubmed:language | eng | lld:pubmed |
pubmed-article:7906328 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7906328 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:7906328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:7906328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7906328 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7906328 | pubmed:month | Mar | lld:pubmed |
pubmed-article:7906328 | pubmed:issn | 0140-6736 | lld:pubmed |
pubmed-article:7906328 | pubmed:author | pubmed-author:LongG WGW | lld:pubmed |
pubmed-article:7906328 | pubmed:author | pubmed-author:HoffmanS LSL | lld:pubmed |
pubmed-article:7906328 | pubmed:author | pubmed-author:MaretS MSM | lld:pubmed |
pubmed-article:7906328 | pubmed:author | pubmed-author:BeadleCC | lld:pubmed |
pubmed-article:7906328 | pubmed:author | pubmed-author:WeissW RWR | lld:pubmed |
pubmed-article:7906328 | pubmed:author | pubmed-author:OlooA JAJ | lld:pubmed |
pubmed-article:7906328 | pubmed:author | pubmed-author:McElroyP DPD | lld:pubmed |
pubmed-article:7906328 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7906328 | pubmed:day | 5 | lld:pubmed |
pubmed-article:7906328 | pubmed:volume | 343 | lld:pubmed |
pubmed-article:7906328 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7906328 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7906328 | pubmed:pagination | 564-8 | lld:pubmed |
pubmed-article:7906328 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:7906328 | pubmed:year | 1994 | lld:pubmed |
pubmed-article:7906328 | pubmed:articleTitle | Diagnosis of malaria by detection of Plasmodium falciparum HRP-2 antigen with a rapid dipstick antigen-capture assay. | lld:pubmed |
pubmed-article:7906328 | pubmed:affiliation | Malaria Program, Naval Medical Research Institute, Rockville, MD 20852-1820. | lld:pubmed |
pubmed-article:7906328 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:7906328 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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