| pubmed-article:7901273 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7901273 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:7901273 | lifeskim:mentions | umls-concept:C0314787 | lld:lifeskim |
| pubmed-article:7901273 | lifeskim:mentions | umls-concept:C0012652 | lld:lifeskim |
| pubmed-article:7901273 | lifeskim:mentions | umls-concept:C0012854 | lld:lifeskim |
| pubmed-article:7901273 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:7901273 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:7901273 | pubmed:dateCreated | 1993-12-9 | lld:pubmed |
| pubmed-article:7901273 | pubmed:abstractText | The prevalence of nosocomial acinetobacter colonization and infection in a university hospital was reviewed and multiresistant Acinetobacter baumannii infections in an intensive care unit (ICU) were investigated using epidemiological typing and a case-control study. Acinetobacter colonization at various body sites was found in 3.2 to 10.8 per 1000 patients. Acinetobacter infection accounted for 0.3% of endemic nosocomial infections in critically ill patients and for 1% of nosocomial bacteraemia hospitalwide. Over a three-week period, four ventilated patients developed colonization, followed by pneumonia in two patients, with A. baumannii resistant to multiple antimicrobials. Cultures of samples from respiratory equipment and ICU surfaces (n = 27) as well as from hands of personnel (n = 14) failed to yield A. baumannii, except for one sample of respiratory tubing. Antibiogram, biotype, chromosomal DNA macrorestriction profiles and polymerase chain reaction (PCR) mediated fingerprints of A. baumannii isolates (n = 31) indicated that this outbreak was caused by two strains, one of which later spread to another hospital where it caused a second outbreak. Both strains were clearly discriminated from control strains from cases of sporadic infection. Risk factors for cross-colonization that were identified by a case-control comparison were neurosurgery, mechanical ventilation and treatment with broad-spectrum antibiotics. Transmission was controlled by implementing contact isolation precautions and routine sterilization of ventilator tubing. Wider use of sensitive genotypic methods like DNA macrorestriction analysis and PCR-mediated fingerprinting for typing nosocomial pathogens should improve the detection of micro-epidemics amenable to early control. | lld:pubmed |
| pubmed-article:7901273 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7901273 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7901273 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7901273 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7901273 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7901273 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:7901273 | pubmed:issn | 0195-6701 | lld:pubmed |
| pubmed-article:7901273 | pubmed:author | pubmed-author:CarlierEE | lld:pubmed |
| pubmed-article:7901273 | pubmed:author | pubmed-author:van BelkumAA | lld:pubmed |
| pubmed-article:7901273 | pubmed:author | pubmed-author:QuintW GWG | lld:pubmed |
| pubmed-article:7901273 | pubmed:author | pubmed-author:MaerMM | lld:pubmed |
| pubmed-article:7901273 | pubmed:author | pubmed-author:StruelensM... | lld:pubmed |
| pubmed-article:7901273 | pubmed:author | pubmed-author:SerruysEE | lld:pubmed |
| pubmed-article:7901273 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7901273 | pubmed:volume | 25 | lld:pubmed |
| pubmed-article:7901273 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7901273 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7901273 | pubmed:pagination | 15-32 | lld:pubmed |
| pubmed-article:7901273 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:7901273 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:7901273 | pubmed:articleTitle | Nosocomial colonization and infection with multiresistant Acinetobacter baumannii: outbreak delineation using DNA macrorestriction analysis and PCR-fingerprinting. | lld:pubmed |
| pubmed-article:7901273 | pubmed:affiliation | Department of Microbiology, Hospital Epidemiology, Bruxelles, Belgium. | lld:pubmed |
| pubmed-article:7901273 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7901273 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:7901273 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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