pubmed-article:7885450 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7885450 | lifeskim:mentions | umls-concept:C0172237 | lld:lifeskim |
pubmed-article:7885450 | lifeskim:mentions | umls-concept:C1413181 | lld:lifeskim |
pubmed-article:7885450 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
pubmed-article:7885450 | lifeskim:mentions | umls-concept:C1711351 | lld:lifeskim |
pubmed-article:7885450 | pubmed:issue | 6519 | lld:pubmed |
pubmed-article:7885450 | pubmed:dateCreated | 1995-4-12 | lld:pubmed |
pubmed-article:7885450 | pubmed:abstractText | The RNA polymerase II large subunit contains an essential carboxy-terminal domain (CTD) believed to be involved in the response to regulators during transcription initiation. The CTD is phosphorylated on a portion of RNA polymerase II molecules in vivo and it can be phosphorylated by the general transcription factor TFIIH in vitro. A highly purified TFIIH from rat liver has been described; this, like human and yeast TFIIH, contains associated CTD kinase and helicase activities. We report here that two polypeptides of the purified mammalian TFIIH are the MO15/Cdk7 kinase and cyclin H subunits of the Cdk-activating kinase Cak, previously identified as a positive regulator of Cdc2 and Cdk2. TFIIH and Cak preparations are each capable of phosphorylating recombinant CTD and recombinant Cdk2 proteins. The presence of Cak in TFIIH indicates that Cak may have roles in transcriptional regulation and in cell-cycle control. | lld:pubmed |
pubmed-article:7885450 | pubmed:language | eng | lld:pubmed |
pubmed-article:7885450 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7885450 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7885450 | pubmed:month | Mar | lld:pubmed |
pubmed-article:7885450 | pubmed:issn | 0028-0836 | lld:pubmed |
pubmed-article:7885450 | pubmed:author | pubmed-author:YoungR ARA | lld:pubmed |
pubmed-article:7885450 | pubmed:author | pubmed-author:WeinbergR ARA | lld:pubmed |
pubmed-article:7885450 | pubmed:author | pubmed-author:MäkeläT PTP | lld:pubmed |
pubmed-article:7885450 | pubmed:author | pubmed-author:SerizawaHH | lld:pubmed |
pubmed-article:7885450 | pubmed:author | pubmed-author:ConawayR CRC | lld:pubmed |
pubmed-article:7885450 | pubmed:author | pubmed-author:ConawayJ WJW | lld:pubmed |
pubmed-article:7885450 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7885450 | pubmed:day | 16 | lld:pubmed |
pubmed-article:7885450 | pubmed:volume | 374 | lld:pubmed |
pubmed-article:7885450 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7885450 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7885450 | pubmed:pagination | 280-2 | lld:pubmed |
pubmed-article:7885450 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:meshHeading | pubmed-meshheading:7885450-... | lld:pubmed |
pubmed-article:7885450 | pubmed:year | 1995 | lld:pubmed |
pubmed-article:7885450 | pubmed:articleTitle | Association of Cdk-activating kinase subunits with transcription factor TFIIH. | lld:pubmed |
pubmed-article:7885450 | pubmed:affiliation | Whitehead Institute for Biomedical Research, Nine Cambridge Center, Massachusetts 02142. | lld:pubmed |
pubmed-article:7885450 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:7885450 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:7885450 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
entrez-gene:1022 | entrezgene:pubmed | pubmed-article:7885450 | lld:entrezgene |
entrez-gene:171150 | entrezgene:pubmed | pubmed-article:7885450 | lld:entrezgene |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7885450 | lld:pubmed |