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pubmed-article:7871697pubmed:abstractTextThe build up of lungworm infections was studied in four groups of calves. Calves of Group 1 were infected experimentally with 6 x 10 larvae during the first 3 weeks after turnout. The pasture of Group 2 was contaminated with approximately 35,000 larvae in June and the pasture of Group 3 with approximately 1.3 million larvae in August. Group 4 served as the helminth free control group for challenge infections with 5,000 larvae in October. In Group 1 faecal larval counts increased 5 weeks after the beginning of patency and decreased after another 3 weeks, indicating the development of immunity after the second lungworm generation. In contrast, the development of immunity in Groups 2 and 3 occurred after the first lungworm generation as maximal faecal larval counts were seen within 3.5 weeks after the beginning of patency. Infection levels were highest in Group 3 which was the only group showing clinical signs. These signs became worse after oxfendazole treatment.lld:pubmed
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pubmed-article:7871697pubmed:dateRevised2003-11-14lld:pubmed
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pubmed-article:7871697pubmed:articleTitleAn experimental field study on the build up of lungworm infections in cattle.lld:pubmed
pubmed-article:7871697pubmed:affiliationDepartment of Infectious Diseases and Immunology, Utrecht University, The Netherlands.lld:pubmed
pubmed-article:7871697pubmed:publicationTypeJournal Articlelld:pubmed