| pubmed-article:7856292 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C0042776 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C0021400 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C0039195 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C0028612 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C0030956 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C0038952 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C0178602 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C0805586 | lld:lifeskim |
| pubmed-article:7856292 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:7856292 | pubmed:issue | 14 | lld:pubmed |
| pubmed-article:7856292 | pubmed:dateCreated | 1995-3-16 | lld:pubmed |
| pubmed-article:7856292 | pubmed:abstractText | Even though virus-induced cytotoxic T lymphocytes (CTLs) recognize antigens as peptides presented on infected cells, short synthetic peptides without any modifications are generally considered unsuitable for inducing antigen-specific CTLs in vivo. Our results demonstrate rapid induction of influenza virus-specific CTLs in Balb/c mice by an unmodified core protein peptide known to be a dominant H-2d-restricted CTL epitope. Additionally, the immunization procedure we employed in these studies produced significant influenza virus-specific CTLs in lymph nodes, spleen and lungs. When challenged with a lethal dose of influenza virus, a statistically significant delay in the day of death was observed in peptide-immunized mice. However, viral clearance was only slightly different from that in control mice. While these results are encouraging, they suggest a requirement for multiple CTL-inducing peptides, helper T cell-inducing peptides and/or virus-specific IgA responses in order to achieve protection from influenza infection. | lld:pubmed |
| pubmed-article:7856292 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7856292 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7856292 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7856292 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7856292 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7856292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7856292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7856292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7856292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7856292 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7856292 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:7856292 | pubmed:issn | 0264-410X | lld:pubmed |
| pubmed-article:7856292 | pubmed:author | pubmed-author:ArlinghausR... | lld:pubmed |
| pubmed-article:7856292 | pubmed:author | pubmed-author:SmallP APAJr | lld:pubmed |
| pubmed-article:7856292 | pubmed:author | pubmed-author:BellWW | lld:pubmed |
| pubmed-article:7856292 | pubmed:author | pubmed-author:SastryK JKJ | lld:pubmed |
| pubmed-article:7856292 | pubmed:author | pubmed-author:BenderB SBS | lld:pubmed |
| pubmed-article:7856292 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7856292 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:7856292 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7856292 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7856292 | pubmed:pagination | 1281-7 | lld:pubmed |
| pubmed-article:7856292 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7856292 | pubmed:meshHeading | pubmed-meshheading:7856292-... | lld:pubmed |
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| pubmed-article:7856292 | pubmed:meshHeading | pubmed-meshheading:7856292-... | lld:pubmed |
| pubmed-article:7856292 | pubmed:meshHeading | pubmed-meshheading:7856292-... | lld:pubmed |
| pubmed-article:7856292 | pubmed:meshHeading | pubmed-meshheading:7856292-... | lld:pubmed |
| pubmed-article:7856292 | pubmed:meshHeading | pubmed-meshheading:7856292-... | lld:pubmed |
| pubmed-article:7856292 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:7856292 | pubmed:articleTitle | Effects of influenza virus-specific cytotoxic T-lymphocyte responses induced by a synthetic nucleoprotein peptide on the survival of mice challenged with a lethal dose of virus. | lld:pubmed |
| pubmed-article:7856292 | pubmed:affiliation | Department of Molecular Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030. | lld:pubmed |
| pubmed-article:7856292 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7856292 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:7856292 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:7856292 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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