| pubmed-article:7825462 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7825462 | lifeskim:mentions | umls-concept:C0020517 | lld:lifeskim |
| pubmed-article:7825462 | lifeskim:mentions | umls-concept:C0012155 | lld:lifeskim |
| pubmed-article:7825462 | lifeskim:mentions | umls-concept:C0026724 | lld:lifeskim |
| pubmed-article:7825462 | lifeskim:mentions | umls-concept:C0021853 | lld:lifeskim |
| pubmed-article:7825462 | lifeskim:mentions | umls-concept:C0029923 | lld:lifeskim |
| pubmed-article:7825462 | lifeskim:mentions | umls-concept:C0015689 | lld:lifeskim |
| pubmed-article:7825462 | lifeskim:mentions | umls-concept:C1416902 | lld:lifeskim |
| pubmed-article:7825462 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:7825462 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:7825462 | lifeskim:mentions | umls-concept:C1512943 | lld:lifeskim |
| pubmed-article:7825462 | lifeskim:mentions | umls-concept:C1883709 | lld:lifeskim |
| pubmed-article:7825462 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:7825462 | pubmed:dateCreated | 1995-2-14 | lld:pubmed |
| pubmed-article:7825462 | pubmed:abstractText | In order to clarify the mechanisms of food-sensitive enteropathy, a food hypersensitive model was generated by feeding ovalbumin to female BALB/c mice after intraperitoneal injection of cyclophosphamide and morphological and immunological changes in the gut mucosa were investigated. Villus atrophy, crypt hyperplasia and increased numbers of intra-epithelial lymphocytes (IEL) were confirmed in this model, as seen in food-sensitive enteropathy in humans. Subpopulations of IEL and lamina propria lymphocytes were enumerated by immunohistochemical observation. CD8-positive cells were increased both in epithelium and lamina propria, whereas CD4-positive cells were decreased in lamina propria. We document here that orally administered food antigen actually induces food-sensitive enteropathy and mucosal damage is generated by lymphocytes that infiltrate the intestinal mucosa. We also investigated the effect of feeding an omega-3 fatty acid-enriched diet in this model and found that it was efficient in attenuating mucosal damage. | lld:pubmed |
| pubmed-article:7825462 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7825462 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7825462 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7825462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7825462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7825462 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7825462 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:7825462 | pubmed:issn | 0374-5600 | lld:pubmed |
| pubmed-article:7825462 | pubmed:author | pubmed-author:OhtsukaYY | lld:pubmed |
| pubmed-article:7825462 | pubmed:author | pubmed-author:YamashiroYY | lld:pubmed |
| pubmed-article:7825462 | pubmed:author | pubmed-author:YabutaKK | lld:pubmed |
| pubmed-article:7825462 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7825462 | pubmed:volume | 36 | lld:pubmed |
| pubmed-article:7825462 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7825462 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7825462 | pubmed:pagination | 550-6 | lld:pubmed |
| pubmed-article:7825462 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7825462 | pubmed:meshHeading | pubmed-meshheading:7825462-... | lld:pubmed |
| pubmed-article:7825462 | pubmed:meshHeading | pubmed-meshheading:7825462-... | lld:pubmed |
| pubmed-article:7825462 | pubmed:meshHeading | pubmed-meshheading:7825462-... | lld:pubmed |
| pubmed-article:7825462 | pubmed:meshHeading | pubmed-meshheading:7825462-... | lld:pubmed |
| pubmed-article:7825462 | pubmed:meshHeading | pubmed-meshheading:7825462-... | lld:pubmed |
| pubmed-article:7825462 | pubmed:meshHeading | pubmed-meshheading:7825462-... | lld:pubmed |
| pubmed-article:7825462 | pubmed:meshHeading | pubmed-meshheading:7825462-... | lld:pubmed |
| pubmed-article:7825462 | pubmed:meshHeading | pubmed-meshheading:7825462-... | lld:pubmed |
| pubmed-article:7825462 | pubmed:meshHeading | pubmed-meshheading:7825462-... | lld:pubmed |
| pubmed-article:7825462 | pubmed:meshHeading | pubmed-meshheading:7825462-... | lld:pubmed |
| pubmed-article:7825462 | pubmed:meshHeading | pubmed-meshheading:7825462-... | lld:pubmed |
| pubmed-article:7825462 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:7825462 | pubmed:articleTitle | The regulation of intestinal hypersensitivity reactions to ovalbumin by omega-3 fatty acid enriched diet: studies of IEL and LPL in mucosal damage. | lld:pubmed |
| pubmed-article:7825462 | pubmed:affiliation | Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan. | lld:pubmed |
| pubmed-article:7825462 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7825462 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
