| pubmed-article:7822317 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7822317 | lifeskim:mentions | umls-concept:C0031715 | lld:lifeskim |
| pubmed-article:7822317 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:7822317 | pubmed:dateCreated | 1995-2-13 | lld:pubmed |
| pubmed-article:7822317 | pubmed:abstractText | To gain insight into the abnormal phosphorylation of PHF-tau, we have determined the phosphorylation sites by identifying phosphopeptides by means of ion spray mass spectrometry followed by sequencing of ethane-thiol-modified peptides. Nineteen sites have been identified; all but Ser-262 are localized to the amino- and carboxyl-terminal flanking regions of the microtubule-binding domain. Eleven sites correspond to fetal type sites. Unexpectedly, 10 are non-proline-directed, whereas the others are proline-directed. Thus, the abnormal phosphorylation of PHF-tau can be considered to consist of fetal type phosphorylation and additional proline-directed and non-proline-directed phosphorylation. This non-fetal type phosphorylation may provide PHF-tau with the unusual characteristics. | lld:pubmed |
| pubmed-article:7822317 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7822317 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7822317 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7822317 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7822317 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7822317 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7822317 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7822317 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:7822317 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:7822317 | pubmed:author | pubmed-author:SuzukiMM | lld:pubmed |
| pubmed-article:7822317 | pubmed:author | pubmed-author:YoshidaHH | lld:pubmed |
| pubmed-article:7822317 | pubmed:author | pubmed-author:HasegawaMM | lld:pubmed |
| pubmed-article:7822317 | pubmed:author | pubmed-author:IharaYY | lld:pubmed |
| pubmed-article:7822317 | pubmed:author | pubmed-author:TitaniKK | lld:pubmed |
| pubmed-article:7822317 | pubmed:author | pubmed-author:TakioKK | lld:pubmed |
| pubmed-article:7822317 | pubmed:author | pubmed-author:Morishima-Kaw... | lld:pubmed |
| pubmed-article:7822317 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7822317 | pubmed:day | 13 | lld:pubmed |
| pubmed-article:7822317 | pubmed:volume | 270 | lld:pubmed |
| pubmed-article:7822317 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7822317 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7822317 | pubmed:pagination | 823-9 | lld:pubmed |
| pubmed-article:7822317 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7822317 | pubmed:meshHeading | pubmed-meshheading:7822317-... | lld:pubmed |
| pubmed-article:7822317 | pubmed:meshHeading | pubmed-meshheading:7822317-... | lld:pubmed |
| pubmed-article:7822317 | pubmed:meshHeading | pubmed-meshheading:7822317-... | lld:pubmed |
| pubmed-article:7822317 | pubmed:meshHeading | pubmed-meshheading:7822317-... | lld:pubmed |
| pubmed-article:7822317 | pubmed:meshHeading | pubmed-meshheading:7822317-... | lld:pubmed |
| pubmed-article:7822317 | pubmed:meshHeading | pubmed-meshheading:7822317-... | lld:pubmed |
| pubmed-article:7822317 | pubmed:meshHeading | pubmed-meshheading:7822317-... | lld:pubmed |
| pubmed-article:7822317 | pubmed:meshHeading | pubmed-meshheading:7822317-... | lld:pubmed |
| pubmed-article:7822317 | pubmed:meshHeading | pubmed-meshheading:7822317-... | lld:pubmed |
| pubmed-article:7822317 | pubmed:meshHeading | pubmed-meshheading:7822317-... | lld:pubmed |
| pubmed-article:7822317 | pubmed:meshHeading | pubmed-meshheading:7822317-... | lld:pubmed |
| pubmed-article:7822317 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7822317 | pubmed:articleTitle | Proline-directed and non-proline-directed phosphorylation of PHF-tau. | lld:pubmed |
| pubmed-article:7822317 | pubmed:affiliation | Department of Neuropathology, Faculty of Medicine, University of Tokyo, Japan. | lld:pubmed |
| pubmed-article:7822317 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7822317 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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