| pubmed-article:7822272 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7822272 | lifeskim:mentions | umls-concept:C0440744 | lld:lifeskim |
| pubmed-article:7822272 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:7822272 | lifeskim:mentions | umls-concept:C0108471 | lld:lifeskim |
| pubmed-article:7822272 | lifeskim:mentions | umls-concept:C0205227 | lld:lifeskim |
| pubmed-article:7822272 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:7822272 | pubmed:dateCreated | 1995-2-13 | lld:pubmed |
| pubmed-article:7822272 | pubmed:abstractText | An enzyme hydrolyzing the carboxyl terminus of endothelin-1 was detected in control human tissues but was deficient in tissues from a patient with galactosialidosis, a metabolic disease caused by the protective protein gene mutation. It was proportional to the amount of immunologically estimated mature protective protein. An antibody against the lysosomal protective protein/beta-galactosidase complex precipitated the enzyme activity almost completely. Transfection of the human cDNA for protective protein resulted in high expression of the enzyme activity in transformed fibroblasts from a galactosialidosis patient. These results indicated that the mature protective protein is a major soluble endogenous endothelin degradation enzyme in human tissues. | lld:pubmed |
| pubmed-article:7822272 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7822272 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7822272 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7822272 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7822272 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7822272 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7822272 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7822272 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7822272 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7822272 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7822272 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7822272 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:7822272 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:7822272 | pubmed:author | pubmed-author:SuzukiYY | lld:pubmed |
| pubmed-article:7822272 | pubmed:author | pubmed-author:ItohKK | lld:pubmed |
| pubmed-article:7822272 | pubmed:author | pubmed-author:FüsyFF | lld:pubmed |
| pubmed-article:7822272 | pubmed:author | pubmed-author:SakurabaHH | lld:pubmed |
| pubmed-article:7822272 | pubmed:author | pubmed-author:SatakeAA | lld:pubmed |
| pubmed-article:7822272 | pubmed:author | pubmed-author:ShimmotoMM | lld:pubmed |
| pubmed-article:7822272 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7822272 | pubmed:day | 13 | lld:pubmed |
| pubmed-article:7822272 | pubmed:volume | 270 | lld:pubmed |
| pubmed-article:7822272 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7822272 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7822272 | pubmed:pagination | 515-8 | lld:pubmed |
| pubmed-article:7822272 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:7822272 | pubmed:meshHeading | pubmed-meshheading:7822272-... | lld:pubmed |
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| pubmed-article:7822272 | pubmed:meshHeading | pubmed-meshheading:7822272-... | lld:pubmed |
| pubmed-article:7822272 | pubmed:meshHeading | pubmed-meshheading:7822272-... | lld:pubmed |
| pubmed-article:7822272 | pubmed:meshHeading | pubmed-meshheading:7822272-... | lld:pubmed |
| pubmed-article:7822272 | pubmed:meshHeading | pubmed-meshheading:7822272-... | lld:pubmed |
| pubmed-article:7822272 | pubmed:meshHeading | pubmed-meshheading:7822272-... | lld:pubmed |
| pubmed-article:7822272 | pubmed:meshHeading | pubmed-meshheading:7822272-... | lld:pubmed |
| pubmed-article:7822272 | pubmed:meshHeading | pubmed-meshheading:7822272-... | lld:pubmed |
| pubmed-article:7822272 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7822272 | pubmed:articleTitle | Protective protein as an endogenous endothelin degradation enzyme in human tissues. | lld:pubmed |
| pubmed-article:7822272 | pubmed:affiliation | Department of Clinical Genetics, Tokyo Metropolitan Institute of Medical Science, Japan. | lld:pubmed |
| pubmed-article:7822272 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7822272 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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