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pubmed-article:7766002pubmed:abstractTextThree cytotoxic clerodane diterpenes were purified from an ethyl acetate-soluble extract of the stem bark of Polyalthia barnesii, namely, 16 alpha-hydroxycleroda-3,13(14)Z-dien-15,16-olide, a known compound, and two novel compounds, 3 beta, 16 alpha-dihydroxycleroda-4(18),13(14)Z-dien-15,16-olide and 4 beta, 16 alpha-dihydroxyclerod-13(14)Z-en-15,16-olide. These compounds were found to exhibit broad cytotoxicity against a panel of human cancer cell lines.lld:pubmed
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pubmed-article:7766002pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:7766002pubmed:articleTitleCytotoxic clerodane diterpenes from Polyalthia barnesii.lld:pubmed
pubmed-article:7766002pubmed:affiliationDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago 60612, USA.lld:pubmed
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