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pubmed-article:7760083pubmed:abstractTextNear-infrared spectroscopy (NIRS) is an emerging technique for noninvasive, bedside monitoring of cerebral oxygenation and blood flow. Traditionally, it has relied on the Beer's Law relationship in which the concentration of light-absorbing oxygen-carrying pigments is proportional to their light absorbance, and inversely proportional to an optical path length (a measure of the distance traveled by photons passing through the tissue). In practice, NIRS has been based upon assumptions that mean transcranial optical path length, the average optical path length for a given patient, is constant among patients and independent of the wavelength of light used.lld:pubmed
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pubmed-article:7760083pubmed:articleTitleTranscranial optical path length in infants by near-infrared phase-shift spectroscopy.lld:pubmed
pubmed-article:7760083pubmed:affiliationDepartment of Anesthesiology, University of Pennsylvania School of Medicine, Philadelphia, USA.lld:pubmed
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