| pubmed-article:7759950 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7759950 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:7759950 | lifeskim:mentions | umls-concept:C0330390 | lld:lifeskim |
| pubmed-article:7759950 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:7759950 | lifeskim:mentions | umls-concept:C1749467 | lld:lifeskim |
| pubmed-article:7759950 | lifeskim:mentions | umls-concept:C1415900 | lld:lifeskim |
| pubmed-article:7759950 | lifeskim:mentions | umls-concept:C0376315 | lld:lifeskim |
| pubmed-article:7759950 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:7759950 | pubmed:dateCreated | 1995-6-28 | lld:pubmed |
| pubmed-article:7759950 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7759950 | pubmed:abstractText | The recently cloned ligand binding component of the type I human interferon-alpha/beta receptor (IFN-alpha/beta R) and its soluble analogue (p40) were characterized. p40 is a potent inhibitor of type I IFNs and antibodies directed against p40 completely block the activity of type I IFNs in human cells. These antibodies immunoprecipitate cellular 102-kDa (major) and 51-kDa (minor) forms of IFN-alpha/beta R. We find that the 51-kDa IFN-alpha/beta R. Two types of cDNA clones were isolated and sequenced, a 1.5-kb cDNA coding for the transmembrane 51-kDa IFN-alpha/beta R and a 4.5-kb cDNA coding for p40. In addition to ligand binding, IFN-alpha/beta R is directly involved in signaling, because it becomes phosphorylated at Tyr residues on ligand binding and it is physically associated with the cytoplasmic tyrosine kinase JAK1. | lld:pubmed |
| pubmed-article:7759950 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7759950 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7759950 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7759950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7759950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7759950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7759950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7759950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7759950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7759950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7759950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7759950 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7759950 | pubmed:month | May | lld:pubmed |
| pubmed-article:7759950 | pubmed:issn | 0741-5400 | lld:pubmed |
| pubmed-article:7759950 | pubmed:author | pubmed-author:TaiMM | lld:pubmed |
| pubmed-article:7759950 | pubmed:author | pubmed-author:RubinsteinMM | lld:pubmed |
| pubmed-article:7759950 | pubmed:author | pubmed-author:CohenBB | lld:pubmed |
| pubmed-article:7759950 | pubmed:author | pubmed-author:NovickDD | lld:pubmed |
| pubmed-article:7759950 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7759950 | pubmed:volume | 57 | lld:pubmed |
| pubmed-article:7759950 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7759950 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7759950 | pubmed:pagination | 712-8 | lld:pubmed |
| pubmed-article:7759950 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:7759950 | pubmed:meshHeading | pubmed-meshheading:7759950-... | lld:pubmed |
| pubmed-article:7759950 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7759950 | pubmed:articleTitle | Soluble and membrane-anchored forms of the human IFN-alpha/beta receptor. | lld:pubmed |
| pubmed-article:7759950 | pubmed:affiliation | Department of Molecular Genetics and Virology, Weizmann Institute of Science, Rehovot, Israel. | lld:pubmed |
| pubmed-article:7759950 | pubmed:publicationType | Journal Article | lld:pubmed |
| literatureCitation:428_7759... | literatureCitation:pubmed | pubmed-article:7759950 | lld:drugbank |
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