[A case of primary orbital lymphoma with macroglobulinemia].

Source:http://linkedlifedata.com/resource/pubmed/id/7741066

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Authors

Fujimoto S, Matsuo N, Mori S, Ohshima K, Hoshida Y, Kirk DB

Affiliation

Department of Ophthalmology, Kobe West City Hospital, Japan.

Abstract

A rare case of primary orbital lymphoma with macroglobulinemia was reported. The patient was a 74-year-old male with bilateral orbital tumor. Exophthalmos and eye movement disturbance appeared in his left eye. Blood analysis showed a marked increase of serum immunoglobulin M. Immunochemical study showed 7,097 (mg/dl). The left tumor was partially removed and examined histopathologically and immunohistochemically. H.E. staining revealed the proliferation of lymphoplasmacytoid cells. Immunocytochemical staining showed these cells to be immunoglobulin G (-), immunoglobulin A (-), immunoglobulin M (+), immunoglobulin light chi-chain (-), immunoglobulin light lambda-chain (+), LCA (+), L-26(PAN-B)(+), MT-1(-), and UCHL(-). Based on these results, our diagnosis was non-Hodgkin's lymphoma of the diffuse small, lymphoplasmacytoid type.

PMID
7741066

Publication types

English Abstract; Case Reports