| pubmed-article:7715296 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7715296 | lifeskim:mentions | umls-concept:C0002395 | lld:lifeskim |
| pubmed-article:7715296 | lifeskim:mentions | umls-concept:C0002726 | lld:lifeskim |
| pubmed-article:7715296 | lifeskim:mentions | umls-concept:C0003595 | lld:lifeskim |
| pubmed-article:7715296 | pubmed:issue | 8955 | lld:pubmed |
| pubmed-article:7715296 | pubmed:dateCreated | 1995-5-18 | lld:pubmed |
| pubmed-article:7715296 | pubmed:abstractText | The presence of the apolipoprotein E4 allele has been identified as a major risk factor for late-onset Alzheimer's disease. Apolipoprotein E has also been found immunohistochemically in Alzheimer's disease lesions. We biochemically isolated amyloid beta from senile plaques and found that a carboxyl-terminal fragment (residues 216-299) of apolipoprotein E co-purified. In vitro this fragment from recombinant apolipoprotein E could form amyloid-like fibrils, which were Congo-red positive. Thus senile plaques may contain both amyloid beta and apolipoprotein E amyloid fibrils. | lld:pubmed |
| pubmed-article:7715296 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7715296 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7715296 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7715296 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7715296 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7715296 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:7715296 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7715296 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7715296 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7715296 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:7715296 | pubmed:issn | 0140-6736 | lld:pubmed |
| pubmed-article:7715296 | pubmed:author | pubmed-author:FrangioneBB | lld:pubmed |
| pubmed-article:7715296 | pubmed:author | pubmed-author:VogelTT | lld:pubmed |
| pubmed-article:7715296 | pubmed:author | pubmed-author:GolabekAA | lld:pubmed |
| pubmed-article:7715296 | pubmed:author | pubmed-author:WisniewskiTT | lld:pubmed |
| pubmed-article:7715296 | pubmed:author | pubmed-author:LalowskiMM | lld:pubmed |
| pubmed-article:7715296 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7715296 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:7715296 | pubmed:volume | 345 | lld:pubmed |
| pubmed-article:7715296 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7715296 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7715296 | pubmed:pagination | 956-8 | lld:pubmed |
| pubmed-article:7715296 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:7715296 | pubmed:meshHeading | pubmed-meshheading:7715296-... | lld:pubmed |
| pubmed-article:7715296 | pubmed:meshHeading | pubmed-meshheading:7715296-... | lld:pubmed |
| pubmed-article:7715296 | pubmed:meshHeading | pubmed-meshheading:7715296-... | lld:pubmed |
| pubmed-article:7715296 | pubmed:meshHeading | pubmed-meshheading:7715296-... | lld:pubmed |
| pubmed-article:7715296 | pubmed:meshHeading | pubmed-meshheading:7715296-... | lld:pubmed |
| pubmed-article:7715296 | pubmed:meshHeading | pubmed-meshheading:7715296-... | lld:pubmed |
| pubmed-article:7715296 | pubmed:meshHeading | pubmed-meshheading:7715296-... | lld:pubmed |
| pubmed-article:7715296 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7715296 | pubmed:articleTitle | Is Alzheimer's disease an apolipoprotein E amyloidosis? | lld:pubmed |
| pubmed-article:7715296 | pubmed:affiliation | Department of Pathology, New York University Medical Center, New York 10016, USA. | lld:pubmed |
| pubmed-article:7715296 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7715296 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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