| pubmed-article:7712129 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7712129 | lifeskim:mentions | umls-concept:C0007009 | lld:lifeskim |
| pubmed-article:7712129 | lifeskim:mentions | umls-concept:C0023745 | lld:lifeskim |
| pubmed-article:7712129 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:7712129 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:7712129 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:7712129 | lifeskim:mentions | umls-concept:C0138837 | lld:lifeskim |
| pubmed-article:7712129 | lifeskim:mentions | umls-concept:C1532411 | lld:lifeskim |
| pubmed-article:7712129 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:7712129 | lifeskim:mentions | umls-concept:C0205460 | lld:lifeskim |
| pubmed-article:7712129 | lifeskim:mentions | umls-concept:C1611588 | lld:lifeskim |
| pubmed-article:7712129 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:7712129 | pubmed:dateCreated | 1995-5-18 | lld:pubmed |
| pubmed-article:7712129 | pubmed:abstractText | Replacement of the central amino methylene linkage of C[psi CH2NH]A[psi CH2NH]AX tetrapeptide inhibitors with carbon tethers led to compounds with potency in the nanomolar range. Some of the more potent olefinic compounds inhibit Ras processing in intact v-ras transformed NIH 3T3 cells with IC50 values in the 0.1 to 1 microM range, and inhibit selectively the anchorage-independent growth of H-ras transformed Rat1 cells at 10 microM. | lld:pubmed |
| pubmed-article:7712129 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7712129 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7712129 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7712129 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7712129 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7712129 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7712129 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7712129 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7712129 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:7712129 | pubmed:issn | 0968-0896 | lld:pubmed |
| pubmed-article:7712129 | pubmed:author | pubmed-author:RandsEE | lld:pubmed |
| pubmed-article:7712129 | pubmed:author | pubmed-author:SmithR LRL | lld:pubmed |
| pubmed-article:7712129 | pubmed:author | pubmed-author:OliffA IAI | lld:pubmed |
| pubmed-article:7712129 | pubmed:author | pubmed-author:GrahamS LSL | lld:pubmed |
| pubmed-article:7712129 | pubmed:author | pubmed-author:GibbsJ BJB | lld:pubmed |
| pubmed-article:7712129 | pubmed:author | pubmed-author:WaiJ SJS | lld:pubmed |
| pubmed-article:7712129 | pubmed:author | pubmed-author:FisherT ETE | lld:pubmed |
| pubmed-article:7712129 | pubmed:author | pubmed-author:BambergerD... | lld:pubmed |
| pubmed-article:7712129 | pubmed:author | pubmed-author:PomplianoD... | lld:pubmed |
| pubmed-article:7712129 | pubmed:author | pubmed-author:MosserS DSD | lld:pubmed |
| pubmed-article:7712129 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7712129 | pubmed:volume | 2 | lld:pubmed |
| pubmed-article:7712129 | pubmed:geneSymbol | ras | lld:pubmed |
| pubmed-article:7712129 | pubmed:geneSymbol | H-ras | lld:pubmed |
| pubmed-article:7712129 | pubmed:geneSymbol | v-raf | lld:pubmed |
| pubmed-article:7712129 | pubmed:geneSymbol | v-ras | lld:pubmed |
| pubmed-article:7712129 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7712129 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:7712129 | pubmed:pagination | 939-47 | lld:pubmed |
| pubmed-article:7712129 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:meshHeading | pubmed-meshheading:7712129-... | lld:pubmed |
| pubmed-article:7712129 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:7712129 | pubmed:articleTitle | Synthesis and biological activity of ras farnesyl protein transferase inhibitors. Tetrapeptide analogs with amino methyl and carbon linkages. | lld:pubmed |
| pubmed-article:7712129 | pubmed:affiliation | Department of Medicinal Chemistry, Merck Research Laboratories, West Point, PA 19486. | lld:pubmed |
| pubmed-article:7712129 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7712129 | lld:pubmed |
