| pubmed-article:7706973 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7706973 | lifeskim:mentions | umls-concept:C0026447 | lld:lifeskim |
| pubmed-article:7706973 | lifeskim:mentions | umls-concept:C0006764 | lld:lifeskim |
| pubmed-article:7706973 | lifeskim:mentions | umls-concept:C0010096 | lld:lifeskim |
| pubmed-article:7706973 | lifeskim:mentions | umls-concept:C0439682 | lld:lifeskim |
| pubmed-article:7706973 | lifeskim:mentions | umls-concept:C0035696 | lld:lifeskim |
| pubmed-article:7706973 | lifeskim:mentions | umls-concept:C0021463 | lld:lifeskim |
| pubmed-article:7706973 | lifeskim:mentions | umls-concept:C0050668 | lld:lifeskim |
| pubmed-article:7706973 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:7706973 | lifeskim:mentions | umls-concept:C0443199 | lld:lifeskim |
| pubmed-article:7706973 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:7706973 | lifeskim:mentions | umls-concept:C1711351 | lld:lifeskim |
| pubmed-article:7706973 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:7706973 | pubmed:dateCreated | 1995-5-10 | lld:pubmed |
| pubmed-article:7706973 | pubmed:abstractText | During the luteal phase of the primate ovulatory cycle the predominant inhibin/activin subunit mRNAs produced by the corpus luteum and antral follicles are those for the alpha- and beta B-subunits respectively. The control of expression of these mRNAs and the resultant nature of the endocrine and paracrine signals which they may potentially generate has yet to be elucidated. Inhibin/activin subunit mRNAs may have a role in both the paracrine regulation of follicular and luteal function and modulation of FSH secretion. The aim of this study was to investigate the expression of inhibin/activin subunit mRNAs following luteal regression induced by either withdrawal of LH support (GnRH antagonist treatment), or by a direct inhibitory action (prostaglandin administration). Marmoset monkeys with regular ovulatory cycles were treated on day 8 and 9 of the luteal phase with either GnRH antagonist, prostaglandin or vehicle (n = 3 per group). Ovaries were studied 48 h after onset of treatment (on day 10 of the luteal phase) by hybridizing frozen tissue sections with radiolabelled riboprobes specific to the inhibin/activin alpha-, beta A- and beta B-subunit mRNAs. After autoradiographic exposure, grain concentrations were quantified by image analysis. In corpora lutea from control marmosets there was high expression of alpha-mRNA with only marginal expression of beta B-mRNA. Corpora lutea in animals treated with GnRH antagonist or prostaglandin had markedly reduced expression of alpha-mRNA while beta B-mRNA was unchanged. In controls, all healthy antral follicles exhibited a high level of expression of beta B-mRNA in the granulosa cells and low expression of alpha-mRNA in theca cells.(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:7706973 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7706973 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7706973 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7706973 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7706973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7706973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7706973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7706973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7706973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7706973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7706973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7706973 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7706973 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:7706973 | pubmed:issn | 0022-0795 | lld:pubmed |
| pubmed-article:7706973 | pubmed:author | pubmed-author:LunnS FSF | lld:pubmed |
| pubmed-article:7706973 | pubmed:author | pubmed-author:FraserH MHM | lld:pubmed |
| pubmed-article:7706973 | pubmed:author | pubmed-author:HillierS GSG | lld:pubmed |
| pubmed-article:7706973 | pubmed:author | pubmed-author:WhitelawP FPF | lld:pubmed |
| pubmed-article:7706973 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7706973 | pubmed:volume | 144 | lld:pubmed |
| pubmed-article:7706973 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7706973 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7706973 | pubmed:pagination | 201-8 | lld:pubmed |
| pubmed-article:7706973 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7706973 | pubmed:meshHeading | pubmed-meshheading:7706973-... | lld:pubmed |
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| pubmed-article:7706973 | pubmed:meshHeading | pubmed-meshheading:7706973-... | lld:pubmed |
| pubmed-article:7706973 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7706973 | pubmed:articleTitle | Induced luteal regression: differential effects on follicular and luteal inhibin/activin subunit mRNAs in the marmoset monkey. | lld:pubmed |
| pubmed-article:7706973 | pubmed:affiliation | MRC Reproductive Biology Unit, University of Edinburgh, UK. | lld:pubmed |
| pubmed-article:7706973 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7706973 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
