| pubmed-article:7706786 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7706786 | lifeskim:mentions | umls-concept:C0220806 | lld:lifeskim |
| pubmed-article:7706786 | lifeskim:mentions | umls-concept:C0019061 | lld:lifeskim |
| pubmed-article:7706786 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:7706786 | lifeskim:mentions | umls-concept:C0148323 | lld:lifeskim |
| pubmed-article:7706786 | lifeskim:mentions | umls-concept:C0231441 | lld:lifeskim |
| pubmed-article:7706786 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:7706786 | lifeskim:mentions | umls-concept:C0920321 | lld:lifeskim |
| pubmed-article:7706786 | lifeskim:mentions | umls-concept:C1292733 | lld:lifeskim |
| pubmed-article:7706786 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:7706786 | pubmed:dateCreated | 1995-5-5 | lld:pubmed |
| pubmed-article:7706786 | pubmed:abstractText | A double-blind, placebo-controlled study was conducted to document possible side effects associated with oral consumption of synthetic verotoxin (VT, shiga-like toxin) Pk-trisaccharide receptor sequences attached to Chromosorb (Synsorb-Pk) by healthy adult volunteers. Synsorb-Pk reclaimed from volunteer stool samples was also analyzed to determine if its VT-binding activity was affected by exposure to the pH extremes and digestive processes of the human gastrointestinal tract. No participant reported any Synsorb-Pk-related adverse reactions, and no clinically important trends in laboratory data were evident. Synsorb-Pk recovered from stools retained its ability to absorb VT in polymyxin extracts of VT-producing Escherichia coli and also neutralized VT when mixed in vitro with VT-positive stools from children with hemorrhagic colitis or hemolytic-uremic syndrome (HUS). These results suggest a potential use for Synsorb-Pk in preventing HUS in patients infected with VT-producing E. coli. | lld:pubmed |
| pubmed-article:7706786 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7706786 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7706786 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:7706786 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7706786 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:7706786 | pubmed:issn | 0022-1899 | lld:pubmed |
| pubmed-article:7706786 | pubmed:author | pubmed-author:WellsGG | lld:pubmed |
| pubmed-article:7706786 | pubmed:author | pubmed-author:LiorHH | lld:pubmed |
| pubmed-article:7706786 | pubmed:author | pubmed-author:ArmstrongG... | lld:pubmed |
| pubmed-article:7706786 | pubmed:author | pubmed-author:MacKenzieAA | lld:pubmed |
| pubmed-article:7706786 | pubmed:author | pubmed-author:GoodyerPP | lld:pubmed |
| pubmed-article:7706786 | pubmed:author | pubmed-author:BlanchardCC | lld:pubmed |
| pubmed-article:7706786 | pubmed:author | pubmed-author:TiddMM | lld:pubmed |
| pubmed-article:7706786 | pubmed:author | pubmed-author:KlassenT PTP | lld:pubmed |
| pubmed-article:7706786 | pubmed:author | pubmed-author:OrrbineEE | lld:pubmed |
| pubmed-article:7706786 | pubmed:author | pubmed-author:AuclairFF | lld:pubmed |
| pubmed-article:7706786 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7706786 | pubmed:volume | 171 | lld:pubmed |
| pubmed-article:7706786 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7706786 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:7706786 | pubmed:pagination | 1042-5 | lld:pubmed |
| pubmed-article:7706786 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:7706786 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7706786 | pubmed:articleTitle | A phase I study of chemically synthesized verotoxin (Shiga-like toxin) Pk-trisaccharide receptors attached to chromosorb for preventing hemolytic-uremic syndrome. | lld:pubmed |
| pubmed-article:7706786 | pubmed:affiliation | Canadian Pediatric Kidney Disease Research Centre Synsorb-Pk Study Group, Ottawa. | lld:pubmed |
| pubmed-article:7706786 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7706786 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:7706786 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:7706786 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:7706786 | pubmed:publicationType | Clinical Trial, Phase I | lld:pubmed |
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