| pubmed-article:7702608 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7702608 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:7702608 | lifeskim:mentions | umls-concept:C0012155 | lld:lifeskim |
| pubmed-article:7702608 | lifeskim:mentions | umls-concept:C0030274 | lld:lifeskim |
| pubmed-article:7702608 | lifeskim:mentions | umls-concept:C0017713 | lld:lifeskim |
| pubmed-article:7702608 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:7702608 | lifeskim:mentions | umls-concept:C1420172 | lld:lifeskim |
| pubmed-article:7702608 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:7702608 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:7702608 | pubmed:dateCreated | 1995-5-1 | lld:pubmed |
| pubmed-article:7702608 | pubmed:abstractText | To define the biochemical and molecular basis of high-fat diet to reduce insulin secretion, the present study examined the effect of high-fat diet on the gene expression of pancreatic GLUT2 and glucokinase. Rats were isoenergetically meal-fed a high-fat or a high-carbohydrate diet for 10 weeks. Plasma glucose concentration was higher, whereas insulin concentration was lower in the rats fed a high-fat diet than in the rats fed a high-carbohydrate diet. The level of GLUT2 and glucokinase mRNA in pancreas was significantly decreased in the rats fed a high-fat diet compared with a high-carbohydrate diet. The rates of reduction in plasma insulin level, pancreatic gene expression of GLUT2 and glucokinase by high-fat feeding were about 50%. These results suggest that high-fat feeding impairs signal transduction mechanism in pancreatic beta-cells to reduce insulin secretion in rats. | lld:pubmed |
| pubmed-article:7702608 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7702608 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7702608 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7702608 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7702608 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:7702608 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7702608 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7702608 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7702608 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7702608 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7702608 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:7702608 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:7702608 | pubmed:author | pubmed-author:IwashitaSS | lld:pubmed |
| pubmed-article:7702608 | pubmed:author | pubmed-author:TamuraTT | lld:pubmed |
| pubmed-article:7702608 | pubmed:author | pubmed-author:SuzukiMM | lld:pubmed |
| pubmed-article:7702608 | pubmed:author | pubmed-author:KimYY | lld:pubmed |
| pubmed-article:7702608 | pubmed:author | pubmed-author:TokuyamaKK | lld:pubmed |
| pubmed-article:7702608 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7702608 | pubmed:day | 28 | lld:pubmed |
| pubmed-article:7702608 | pubmed:volume | 208 | lld:pubmed |
| pubmed-article:7702608 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7702608 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7702608 | pubmed:pagination | 1092-8 | lld:pubmed |
| pubmed-article:7702608 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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| pubmed-article:7702608 | pubmed:meshHeading | pubmed-meshheading:7702608-... | lld:pubmed |
| pubmed-article:7702608 | pubmed:meshHeading | pubmed-meshheading:7702608-... | lld:pubmed |
| pubmed-article:7702608 | pubmed:meshHeading | pubmed-meshheading:7702608-... | lld:pubmed |
| pubmed-article:7702608 | pubmed:meshHeading | pubmed-meshheading:7702608-... | lld:pubmed |
| pubmed-article:7702608 | pubmed:meshHeading | pubmed-meshheading:7702608-... | lld:pubmed |
| pubmed-article:7702608 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7702608 | pubmed:articleTitle | Effect of high-fat diet on the gene expression of pancreatic GLUT2 and glucokinase in rats. | lld:pubmed |
| pubmed-article:7702608 | pubmed:affiliation | Laboratory of Biochemistry of Exercise and Nutrition, University of Tsukuba, Japan. | lld:pubmed |
| pubmed-article:7702608 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7702608 | pubmed:publicationType | Comparative Study | lld:pubmed |
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