pubmed-article:7698990 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7698990 | lifeskim:mentions | umls-concept:C0026237 | lld:lifeskim |
pubmed-article:7698990 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
pubmed-article:7698990 | lifeskim:mentions | umls-concept:C1326471 | lld:lifeskim |
pubmed-article:7698990 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
pubmed-article:7698990 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
pubmed-article:7698990 | lifeskim:mentions | umls-concept:C1711351 | lld:lifeskim |
pubmed-article:7698990 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:7698990 | pubmed:dateCreated | 1995-5-3 | lld:pubmed |
pubmed-article:7698990 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7698990 | pubmed:abstractText | By screening a collection of Saccharomyces cerevisiae mutants temperature sensitive for growth on a nonfermentable carbon source, we have isolated a gene (termed MAS37) which encodes a novel receptor for protein import into mitochondria. Mas37p is a 37-kD outer membrane protein with two putative membrane-spanning regions. Inactivation of the MAS37 gene renders cells temperature-sensitive for respiration-driven growth, inhibits import of precursors into isolated mitochondria, and is synthetically lethal with a deletion of one of the genes encoding the import receptors Mas70p or Mas20p. Inactivation of Mas37p with specific antibodies inhibits import of different precursors to different extents; the precursor specificity of Mas37p resembles that of the previously described import receptor Mas70p. Mas70p and Mas37p form a 1:1 complex in detergent extracts of mitochondria and overexpression of one protein enhances that of the other. We suggest that the Mas37p/Mas70p heterodimer functions as a receptor for protein import into yeast mitochondria and that the mitochondrial receptor system consists of hetero-oligomeric subcomplexes with distinct binding activities, but overlapping precursor specificities. | lld:pubmed |
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pubmed-article:7698990 | pubmed:language | eng | lld:pubmed |
pubmed-article:7698990 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7698990 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:7698990 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7698990 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:7698990 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7698990 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7698990 | pubmed:month | Apr | lld:pubmed |
pubmed-article:7698990 | pubmed:issn | 0021-9525 | lld:pubmed |
pubmed-article:7698990 | pubmed:author | pubmed-author:SchatzGG | lld:pubmed |
pubmed-article:7698990 | pubmed:author | pubmed-author:HorstMM | lld:pubmed |
pubmed-article:7698990 | pubmed:author | pubmed-author:PaltaufFF | lld:pubmed |
pubmed-article:7698990 | pubmed:author | pubmed-author:KohlweinS DSD | lld:pubmed |
pubmed-article:7698990 | pubmed:author | pubmed-author:LampingEE | lld:pubmed |
pubmed-article:7698990 | pubmed:author | pubmed-author:LithgowTT | lld:pubmed |
pubmed-article:7698990 | pubmed:author | pubmed-author:JunneTT | lld:pubmed |
pubmed-article:7698990 | pubmed:author | pubmed-author:BakboJ CJC | lld:pubmed |
pubmed-article:7698990 | pubmed:author | pubmed-author:GratzerSS | lld:pubmed |
pubmed-article:7698990 | pubmed:author | pubmed-author:HauckeVV | lld:pubmed |
pubmed-article:7698990 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7698990 | pubmed:volume | 129 | lld:pubmed |
pubmed-article:7698990 | pubmed:geneSymbol | NAS37 | lld:pubmed |
pubmed-article:7698990 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7698990 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7698990 | pubmed:pagination | 25-34 | lld:pubmed |
pubmed-article:7698990 | pubmed:dateRevised | 2010-9-10 | lld:pubmed |
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