| pubmed-article:7689431 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7689431 | lifeskim:mentions | umls-concept:C0166049 | lld:lifeskim |
| pubmed-article:7689431 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:7689431 | lifeskim:mentions | umls-concept:C0442034 | lld:lifeskim |
| pubmed-article:7689431 | lifeskim:mentions | umls-concept:C0033105 | lld:lifeskim |
| pubmed-article:7689431 | lifeskim:mentions | umls-concept:C1096776 | lld:lifeskim |
| pubmed-article:7689431 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:7689431 | pubmed:dateCreated | 1993-9-30 | lld:pubmed |
| pubmed-article:7689431 | pubmed:abstractText | The prevalence of antibodies to the hepatitis C virus (HCV) was determined in 333 peritoneal dialysis (PD) patients from 10 German dialysis units, using an enzyme-linked immunosorbent assay of the second generation (ELISA 2nd gen) which detects antibodies to a structural (C22) and to non-structural (C33c, C100, 5-1-1) recombinant antigens of HCV. Sera from 18/333 (5.4%) patients were anti-HCV positive versus 11/295 (3.7%) when the sera were tested by an ELISA of the first generation (ELISA 1st gen) containing only a nonstructural antigen (C100). In the 18 sera positive by ELISA 2nd gen, antibodies against at least one viral protein were found by recombinant immunoblot assay (RIBA) in 15/333 (4.5%) patients. In the sera of 11/15 (73.3%) patients HCV RNA was detected by nested PCR. Epidemiological evaluation of the patients revealed that the prevalence of anti-HCV was correlated to the female sex (p = 0.005), presence of anti-HBc (p = 0.006), duration of total dialysis (hemodialysis HD and PD) (p = 0.012), duration of HD alone (p = 0.025) and previous renal transplantation (p < 0.001). Only a weak correlation was found to blood transfusions (p = 0.041) and elevation of serum ALT concentration (p = 0.055). But no correlation was found to diagnoses of renal failure (p = 0.129), duration of PD (p = 0.963) and past surgical procedures (p = 1.0). Four of nine peritoneal dialysates of anti-HCV positive patients were found positive for HCV RNA.(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:7689431 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7689431 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7689431 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7689431 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7689431 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7689431 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7689431 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7689431 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:7689431 | pubmed:issn | 0301-0430 | lld:pubmed |
| pubmed-article:7689431 | pubmed:author | pubmed-author:SieberthH GHG | lld:pubmed |
| pubmed-article:7689431 | pubmed:author | pubmed-author:RoggendorfMM | lld:pubmed |
| pubmed-article:7689431 | pubmed:author | pubmed-author:LorbeerBB | lld:pubmed |
| pubmed-article:7689431 | pubmed:author | pubmed-author:GladziwaUU | lld:pubmed |
| pubmed-article:7689431 | pubmed:author | pubmed-author:SchlipköterUU | lld:pubmed |
| pubmed-article:7689431 | pubmed:author | pubmed-author:CholmakowKK | lld:pubmed |
| pubmed-article:7689431 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7689431 | pubmed:volume | 40 | lld:pubmed |
| pubmed-article:7689431 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7689431 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7689431 | pubmed:pagination | 46-52 | lld:pubmed |
| pubmed-article:7689431 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7689431 | pubmed:meshHeading | pubmed-meshheading:7689431-... | lld:pubmed |
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| pubmed-article:7689431 | pubmed:meshHeading | pubmed-meshheading:7689431-... | lld:pubmed |
| pubmed-article:7689431 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:7689431 | pubmed:articleTitle | Prevalence of antibodies to hepatitis C virus in patients on peritoneal dialysis--a multicenter study. | lld:pubmed |
| pubmed-article:7689431 | pubmed:affiliation | Department of Internal Medicine II, Technical University of Aachen, Germany. | lld:pubmed |
| pubmed-article:7689431 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7689431 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:7689431 | pubmed:publicationType | Multicenter Study | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7689431 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7689431 | lld:pubmed |
