| pubmed-article:7686378 | rdf:type | pubmed:Citation | lld:pubmed |
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| pubmed-article:7686378 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:7686378 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:7686378 | lifeskim:mentions | umls-concept:C0027882 | lld:lifeskim |
| pubmed-article:7686378 | lifeskim:mentions | umls-concept:C0019564 | lld:lifeskim |
| pubmed-article:7686378 | lifeskim:mentions | umls-concept:C0061465 | lld:lifeskim |
| pubmed-article:7686378 | lifeskim:mentions | umls-concept:C1704711 | lld:lifeskim |
| pubmed-article:7686378 | lifeskim:mentions | umls-concept:C0009085 | lld:lifeskim |
| pubmed-article:7686378 | lifeskim:mentions | umls-concept:C1711351 | lld:lifeskim |
| pubmed-article:7686378 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:7686378 | pubmed:dateCreated | 1993-7-30 | lld:pubmed |
| pubmed-article:7686378 | pubmed:abstractText | The distribution of several glutamate receptor subunits was investigated in cultured rat hippocampal neurons by in situ hybridization and immunocytochemistry. The AMPA/kainate-selective receptors GluR1-6 exhibited two patterns of mRNA expression: most neurons expressed GluR1, R2, and R6, whereas only about 20% expressed significant levels of GluR3, R4, and R5. By immunocytochemistry, the metabotropic glutamate receptor mGluR1 alpha was detectable only in a subpopulation of GABAergic interneurons. GluR1 and GluR2/3 segregated to the somatodendritic domain within the first week in culture, even in the absence of synaptogenesis. Glutamate receptor-enriched spines developed later and were present only on presumptive pyramidal cells, not on GABAergic interneurons. Clusters of GluR1 and GluR2/3 completely colocalized and were restricted to a subset of postsynaptic sites. Thus, glutamate receptor subunits exhibit both a cell type-specific expression and a selective subcellular localization. | lld:pubmed |
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| pubmed-article:7686378 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:7686378 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:7686378 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7686378 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:7686378 | pubmed:issn | 0896-6273 | lld:pubmed |
| pubmed-article:7686378 | pubmed:author | pubmed-author:HuganirR LRL | lld:pubmed |
| pubmed-article:7686378 | pubmed:author | pubmed-author:BankerGG | lld:pubmed |
| pubmed-article:7686378 | pubmed:author | pubmed-author:CraigA MAM | lld:pubmed |
| pubmed-article:7686378 | pubmed:author | pubmed-author:BlackstoneC... | lld:pubmed |
| pubmed-article:7686378 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7686378 | pubmed:volume | 10 | lld:pubmed |
| pubmed-article:7686378 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7686378 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7686378 | pubmed:pagination | 1055-68 | lld:pubmed |
| pubmed-article:7686378 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:7686378 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:7686378 | pubmed:articleTitle | The distribution of glutamate receptors in cultured rat hippocampal neurons: postsynaptic clustering of AMPA-selective subunits. | lld:pubmed |
| pubmed-article:7686378 | pubmed:affiliation | Department of Neuroscience, University of Virginia School of Medicine, Charlottesville 22908. | lld:pubmed |
| pubmed-article:7686378 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7686378 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:7686378 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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