| pubmed-article:7627953 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7627953 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:7627953 | lifeskim:mentions | umls-concept:C0006826 | lld:lifeskim |
| pubmed-article:7627953 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:7627953 | lifeskim:mentions | umls-concept:C0018284 | lld:lifeskim |
| pubmed-article:7627953 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:7627953 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:7627953 | pubmed:issue | 16 | lld:pubmed |
| pubmed-article:7627953 | pubmed:dateCreated | 1995-9-7 | lld:pubmed |
| pubmed-article:7627953 | pubmed:abstractText | The Wnt-5A gene codes for a secreted cysteine-rich growth factor that mediates cell to cell signaling via a paracrine mechanism during development and ontogeny. We have recently determine the genomic organization and chromosomal mapping of the human Wnt-5A, and observed distinct patterns of expression in developing human embryos. In this report, we have performed a detailed expression analysis of 100 adult human tissues and tumors and 10 human cell lines. Our data show a widespread expression of Wnt-5A in adult tissues and cells, and aberrant mRNA levels in lungs, breast, and prostate carcinomas and in melanomas. The up-regulation of Wnt-5A in human malignancy was not due to either gene rearrangement or amplification. These findings document an abnormal expression of this growth factor in malignancy and implicate Wnt-5A in the genesis of human cancer. | lld:pubmed |
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| pubmed-article:7627953 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7627953 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7627953 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:7627953 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7627953 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:7627953 | pubmed:issn | 0008-5472 | lld:pubmed |
| pubmed-article:7627953 | pubmed:author | pubmed-author:DanielsonK... | lld:pubmed |
| pubmed-article:7627953 | pubmed:author | pubmed-author:IozzoR VRV | lld:pubmed |
| pubmed-article:7627953 | pubmed:author | pubmed-author:EichstetterII | lld:pubmed |
| pubmed-article:7627953 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7627953 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:7627953 | pubmed:volume | 55 | lld:pubmed |
| pubmed-article:7627953 | pubmed:geneSymbol | Wnt-5a | lld:pubmed |
| pubmed-article:7627953 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7627953 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7627953 | pubmed:pagination | 3495-9 | lld:pubmed |
| pubmed-article:7627953 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7627953 | pubmed:meshHeading | pubmed-meshheading:7627953-... | lld:pubmed |
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| pubmed-article:7627953 | pubmed:meshHeading | pubmed-meshheading:7627953-... | lld:pubmed |
| pubmed-article:7627953 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7627953 | pubmed:articleTitle | Aberrant expression of the growth factor Wnt-5A in human malignancy. | lld:pubmed |
| pubmed-article:7627953 | pubmed:affiliation | Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. | lld:pubmed |
| pubmed-article:7627953 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7627953 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:7627953 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:7627953 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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