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| pubmed-article:7606786 | lifeskim:mentions | umls-concept:C0040649 | lld:lifeskim |
| pubmed-article:7606786 | lifeskim:mentions | umls-concept:C0949662 | lld:lifeskim |
| pubmed-article:7606786 | lifeskim:mentions | umls-concept:C1514562 | lld:lifeskim |
| pubmed-article:7606786 | lifeskim:mentions | umls-concept:C1883221 | lld:lifeskim |
| pubmed-article:7606786 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:7606786 | lifeskim:mentions | umls-concept:C0220905 | lld:lifeskim |
| pubmed-article:7606786 | lifeskim:mentions | umls-concept:C1708111 | lld:lifeskim |
| pubmed-article:7606786 | lifeskim:mentions | umls-concept:C1883204 | lld:lifeskim |
| pubmed-article:7606786 | lifeskim:mentions | umls-concept:C1880389 | lld:lifeskim |
| pubmed-article:7606786 | lifeskim:mentions | umls-concept:C0332453 | lld:lifeskim |
| pubmed-article:7606786 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:7606786 | pubmed:dateCreated | 1995-8-17 | lld:pubmed |
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| pubmed-article:7606786 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7606786 | pubmed:abstractText | Lipomas are one of the most common mesenchymal neoplasms in humans. They are characterized by consistent cytogenetic aberrations involving chromosome 12 in bands q14-15. Interestingly, this region is also the site of rearrangement for other mesenchymally derived tumors. This study demonstrates that HMGI-C, an architectural factor that functions in transcriptional regulation, has been disrupted by rearrangement at the 12q14-15 chromosomal breakpoint in lipomas. Chimeric transcripts were isolated from two lipomas in which HMGI-C DNA-binding domains (AT hook motifs) are fused to either a LIM or an acidic transactivation domain. These results, identifying a gene rearranged in a benign neoplastic process that does not proceed to a malignancy, suggest a role for HMGI-C in adipogenesis and mesenchyme differentiation. | lld:pubmed |
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| pubmed-article:7606786 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7606786 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7606786 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7606786 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7606786 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:7606786 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7606786 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:7606786 | pubmed:issn | 0092-8674 | lld:pubmed |
| pubmed-article:7606786 | pubmed:author | pubmed-author:ZhouXX | lld:pubmed |
| pubmed-article:7606786 | pubmed:author | pubmed-author:WeremowiczSS | lld:pubmed |
| pubmed-article:7606786 | pubmed:author | pubmed-author:FletcherJ AJA | lld:pubmed |
| pubmed-article:7606786 | pubmed:author | pubmed-author:MortonC CCC | lld:pubmed |
| pubmed-article:7606786 | pubmed:author | pubmed-author:ChadaKK | lld:pubmed |
| pubmed-article:7606786 | pubmed:author | pubmed-author:TkachenkoAA | lld:pubmed |
| pubmed-article:7606786 | pubmed:author | pubmed-author:FejzoM SMS | lld:pubmed |
| pubmed-article:7606786 | pubmed:author | pubmed-author:AsharH RHR | lld:pubmed |
| pubmed-article:7606786 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7606786 | pubmed:day | 14 | lld:pubmed |
| pubmed-article:7606786 | pubmed:volume | 82 | lld:pubmed |
| pubmed-article:7606786 | pubmed:geneSymbol | HMGI-C | lld:pubmed |
| pubmed-article:7606786 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7606786 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7606786 | pubmed:pagination | 57-65 | lld:pubmed |
| pubmed-article:7606786 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:7606786 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7606786 | pubmed:articleTitle | Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains. | lld:pubmed |
| pubmed-article:7606786 | pubmed:affiliation | Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway 08854, USA. | lld:pubmed |
| pubmed-article:7606786 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7606786 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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