| pubmed-article:7589067 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7589067 | lifeskim:mentions | umls-concept:C0206745 | lld:lifeskim |
| pubmed-article:7589067 | lifeskim:mentions | umls-concept:C0039195 | lld:lifeskim |
| pubmed-article:7589067 | lifeskim:mentions | umls-concept:C0205147 | lld:lifeskim |
| pubmed-article:7589067 | lifeskim:mentions | umls-concept:C0021027 | lld:lifeskim |
| pubmed-article:7589067 | lifeskim:mentions | umls-concept:C0021036 | lld:lifeskim |
| pubmed-article:7589067 | lifeskim:mentions | umls-concept:C0030956 | lld:lifeskim |
| pubmed-article:7589067 | lifeskim:mentions | umls-concept:C0205171 | lld:lifeskim |
| pubmed-article:7589067 | lifeskim:mentions | umls-concept:C1948059 | lld:lifeskim |
| pubmed-article:7589067 | lifeskim:mentions | umls-concept:C1880371 | lld:lifeskim |
| pubmed-article:7589067 | lifeskim:mentions | umls-concept:C1720529 | lld:lifeskim |
| pubmed-article:7589067 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:7589067 | pubmed:dateCreated | 1995-12-12 | lld:pubmed |
| pubmed-article:7589067 | pubmed:abstractText | Allotype- or idiotype-specific CD4+ T cells have been reported to recognize immunoglobulin (Ig) peptides presented by class II molecules. In contrast, few data are available concerning the generation of Ig peptide-specific CD8+ T cells. We have therefore investigated whether T-depleted spleen cells from Ig kappa light chain-expressing 129/Sv mice (129 kappa +/+) could induce, in C kappa knockout mice (129 kappa -/-), the generation of Ig constant kappa light chain region (C kappa)-specific cytotoxic T lymphocytes (CTL). The determination of TCR beta chain expressed by nine CTL clones, together with the use of a library of overlapping peptides spanning the whole C kappa sequence, show that the B cells from kappa +/+ mice are able to elicit in C kappa knockout mice, the emergence of a diverse CTL repertoire that recognizes one single C kappa peptide presented by the H-2Kb class I molecule. In addition, these data support the notion that B cells are able to process and present on their class I molecules, peptides generated from their own kappa light chains. | lld:pubmed |
| pubmed-article:7589067 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7589067 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7589067 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7589067 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7589067 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7589067 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7589067 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7589067 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7589067 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7589067 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7589067 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:7589067 | pubmed:issn | 0014-2980 | lld:pubmed |
| pubmed-article:7589067 | pubmed:author | pubmed-author:FaureMM | lld:pubmed |
| pubmed-article:7589067 | pubmed:author | pubmed-author:CazenaveP APA | lld:pubmed |
| pubmed-article:7589067 | pubmed:author | pubmed-author:SanchezPP | lld:pubmed |
| pubmed-article:7589067 | pubmed:author | pubmed-author:DrapierA MAM | lld:pubmed |
| pubmed-article:7589067 | pubmed:author | pubmed-author:Rueff-JuyDD | lld:pubmed |
| pubmed-article:7589067 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7589067 | pubmed:volume | 25 | lld:pubmed |
| pubmed-article:7589067 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7589067 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7589067 | pubmed:pagination | 2752-6 | lld:pubmed |
| pubmed-article:7589067 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7589067 | pubmed:meshHeading | pubmed-meshheading:7589067-... | lld:pubmed |
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| pubmed-article:7589067 | pubmed:meshHeading | pubmed-meshheading:7589067-... | lld:pubmed |
| pubmed-article:7589067 | pubmed:meshHeading | pubmed-meshheading:7589067-... | lld:pubmed |
| pubmed-article:7589067 | pubmed:meshHeading | pubmed-meshheading:7589067-... | lld:pubmed |
| pubmed-article:7589067 | pubmed:meshHeading | pubmed-meshheading:7589067-... | lld:pubmed |
| pubmed-article:7589067 | pubmed:meshHeading | pubmed-meshheading:7589067-... | lld:pubmed |
| pubmed-article:7589067 | pubmed:meshHeading | pubmed-meshheading:7589067-... | lld:pubmed |
| pubmed-article:7589067 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7589067 | pubmed:articleTitle | Emergence in C kappa knockout mice of a diverse cytotoxic T lymphocyte repertoire that recognizes a single peptide from the immunoglobulin constant kappa light chain region. | lld:pubmed |
| pubmed-article:7589067 | pubmed:affiliation | Département d'Immunologie, Institut Pasteur (URA CNRS 1961 and Université Pierre et Marie Curie), Paris, France. | lld:pubmed |
| pubmed-article:7589067 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7589067 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
