| pubmed-article:7583792 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7583792 | lifeskim:mentions | umls-concept:C0006675 | lld:lifeskim |
| pubmed-article:7583792 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:7583792 | lifeskim:mentions | umls-concept:C0026649 | lld:lifeskim |
| pubmed-article:7583792 | lifeskim:mentions | umls-concept:C0018787 | lld:lifeskim |
| pubmed-article:7583792 | lifeskim:mentions | umls-concept:C0028351 | lld:lifeskim |
| pubmed-article:7583792 | lifeskim:mentions | umls-concept:C0030685 | lld:lifeskim |
| pubmed-article:7583792 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:7583792 | lifeskim:mentions | umls-concept:C0680255 | lld:lifeskim |
| pubmed-article:7583792 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
| pubmed-article:7583792 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
| pubmed-article:7583792 | lifeskim:mentions | umls-concept:C1963578 | lld:lifeskim |
| pubmed-article:7583792 | lifeskim:mentions | umls-concept:C0443172 | lld:lifeskim |
| pubmed-article:7583792 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:7583792 | pubmed:dateCreated | 1995-12-21 | lld:pubmed |
| pubmed-article:7583792 | pubmed:abstractText | The purpose of this study was to determine if the age-related decrease in norepinephrine (NE) release from cardiac adrenergic nerve terminals is due to a defect in Ca2+ movement into the nerve terminal or to an alteration in Ca2+ activation of intracellular events leading to NE release. NE release was assessed in cardiac synaptosomes prepared from 6- and 24-month-old male F344 rats. K(+)-induced NE release was significantly greater in young vs old rats. Raising extracellular [Ca2+] increased NE release, but NE release always remained higher in the younger animals. Ionomycin, a Ca2+ ionophore, induced NE release from cardiac synaptosomes, and there was no age difference in the response. The age-related reduction in NE release induced by K+ and the capacity of ionomycin to induce similar NE release in young and old cardiac synaptosomes points to a reduction in Ca2+ movement during depolarization. | lld:pubmed |
| pubmed-article:7583792 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7583792 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7583792 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7583792 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7583792 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:7583792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7583792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7583792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7583792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7583792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7583792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7583792 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7583792 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:7583792 | pubmed:issn | 1079-5006 | lld:pubmed |
| pubmed-article:7583792 | pubmed:author | pubmed-author:RobertsJJ | lld:pubmed |
| pubmed-article:7583792 | pubmed:author | pubmed-author:EskinBB | lld:pubmed |
| pubmed-article:7583792 | pubmed:author | pubmed-author:JohnsonM DMD | lld:pubmed |
| pubmed-article:7583792 | pubmed:author | pubmed-author:SnyderD LDL | lld:pubmed |
| pubmed-article:7583792 | pubmed:author | pubmed-author:AloyoVV | lld:pubmed |
| pubmed-article:7583792 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7583792 | pubmed:volume | 50 | lld:pubmed |
| pubmed-article:7583792 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7583792 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7583792 | pubmed:pagination | B358-67 | lld:pubmed |
| pubmed-article:7583792 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:meshHeading | pubmed-meshheading:7583792-... | lld:pubmed |
| pubmed-article:7583792 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7583792 | pubmed:articleTitle | Age-related changes in cardiac norepinephrine release: role of calcium movement. | lld:pubmed |
| pubmed-article:7583792 | pubmed:affiliation | Department of Pharmacology, Medical College of Pennsylvania, Philadelphia, USA. | lld:pubmed |
| pubmed-article:7583792 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7583792 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
