| pubmed-article:7564352 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7564352 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:7564352 | lifeskim:mentions | umls-concept:C0014025 | lld:lifeskim |
| pubmed-article:7564352 | lifeskim:mentions | umls-concept:C0005823 | lld:lifeskim |
| pubmed-article:7564352 | lifeskim:mentions | umls-concept:C0076891 | lld:lifeskim |
| pubmed-article:7564352 | lifeskim:mentions | umls-concept:C1709043 | lld:lifeskim |
| pubmed-article:7564352 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:7564352 | lifeskim:mentions | umls-concept:C0443199 | lld:lifeskim |
| pubmed-article:7564352 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:7564352 | lifeskim:mentions | umls-concept:C0857121 | lld:lifeskim |
| pubmed-article:7564352 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:7564352 | pubmed:dateCreated | 1995-11-22 | lld:pubmed |
| pubmed-article:7564352 | pubmed:abstractText | A double blind randomised comparison of two angiotensin-converting enzyme (ACE) inhibitors was made in a study in which ambulatory blood pressure was monitored over a steady-state dosage interval and the subsequent 24-h period, the latter being designed to mimic a missed dose of drug. The blood pressure responses on active therapy were compared to an identical recording made at the end of a 3-week placebo run in period. Eighty-eight essential hypertensives were treated with a morning dose of either trandolapril 2 mg or enalapril 20 mg. Mean systolic (SBP) and diastolic blood pressure (DBP) were calculated on each of the following periods: daytime (8:31 a.m.-10:30 p.m.), nighttime (10:31 p.m.-6:30 a.m.), and early morning (6:31 a.m.-8:30 a.m.). Trough/peak was calculated for each group both on active treatment and after a missed dose. Twelve patients were excluded from analysis before opening the randomisation code because of inadequate ambulatory blood pressure monitoring (ABPM) recordings. Demographic data, placebo-period office blood pressure, and ABPM recordings were not significantly different between the two groups. Both trandolapril and enalapril effectively reduced blood pressure over the 24-h period. Twenty four-hour ambulatory SBP and DBP decreased from 148 +/- 14/92 +/- 10 mm Hg to 135 +/- 14/83 +/- 10 mm Hg in the trandolapril group (p < 0.001). The same parameters decreased to a quite similar extent after enalapril, from 143 +/- 13/91 +/- 5 mm Hg to 133 +/- 15/83 +/- 8 mm Hg (p < 0.001).(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:7564352 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7564352 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7564352 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7564352 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:7564352 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7564352 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7564352 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:7564352 | pubmed:issn | 0160-2446 | lld:pubmed |
| pubmed-article:7564352 | pubmed:author | pubmed-author:MeredithP APA | lld:pubmed |
| pubmed-article:7564352 | pubmed:author | pubmed-author:ElkikFF | lld:pubmed |
| pubmed-article:7564352 | pubmed:author | pubmed-author:GenesNN | lld:pubmed |
| pubmed-article:7564352 | pubmed:author | pubmed-author:Dutrey-Dupagn... | lld:pubmed |
| pubmed-article:7564352 | pubmed:author | pubmed-author:VauxJJ | lld:pubmed |
| pubmed-article:7564352 | pubmed:author | pubmed-author:Bouvier... | lld:pubmed |
| pubmed-article:7564352 | pubmed:author | pubmed-author:BoussacJJ | lld:pubmed |
| pubmed-article:7564352 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7564352 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:7564352 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7564352 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7564352 | pubmed:pagination | 127-31 | lld:pubmed |
| pubmed-article:7564352 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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| pubmed-article:7564352 | pubmed:meshHeading | pubmed-meshheading:7564352-... | lld:pubmed |
| pubmed-article:7564352 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7564352 | pubmed:articleTitle | Differential effects of a missed dose of trandolapril and enalapril on blood pressure control in hypertensive patients. | lld:pubmed |
| pubmed-article:7564352 | pubmed:affiliation | Medical Department Laboratories, Roussel, Paris. | lld:pubmed |
| pubmed-article:7564352 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7564352 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:7564352 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
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