| pubmed-article:7556103 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7556103 | lifeskim:mentions | umls-concept:C0043393 | lld:lifeskim |
| pubmed-article:7556103 | lifeskim:mentions | umls-concept:C0205103 | lld:lifeskim |
| pubmed-article:7556103 | lifeskim:mentions | umls-concept:C0450429 | lld:lifeskim |
| pubmed-article:7556103 | lifeskim:mentions | umls-concept:C0025186 | lld:lifeskim |
| pubmed-article:7556103 | lifeskim:mentions | umls-concept:C1511667 | lld:lifeskim |
| pubmed-article:7556103 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:7556103 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:7556103 | lifeskim:mentions | umls-concept:C1704666 | lld:lifeskim |
| pubmed-article:7556103 | lifeskim:mentions | umls-concept:C1517892 | lld:lifeskim |
| pubmed-article:7556103 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:7556103 | lifeskim:mentions | umls-concept:C0208973 | lld:lifeskim |
| pubmed-article:7556103 | pubmed:issue | 18 | lld:pubmed |
| pubmed-article:7556103 | pubmed:dateCreated | 1995-11-13 | lld:pubmed |
| pubmed-article:7556103 | pubmed:abstractText | We have determined the precise location and structure of the double-strand DNA breaks (DSBs) formed during Saccharomyces cerevisiae meiosis. Breaks were examined at two recombination hot spots in both wild-type and rad50S mutant cells. At both loci, breaks occurred at multiple, irregularly spaced sites in a approximately 150 nucleotide interval contained within an area of nuclease-hypersensitive chromatin. No consensus sequence could be discerned at or around break sites. Patterns of cleavage observed on individual strands indicated that breaks initially form with a two nucleotide 5' overhang. Broken strands from rad50S mutant cells contained tightly bound protein at their 5' ends. We suggest that, in S.cerevisiae, meiotic recombination is initiated by a DSB-forming activity that creates a covalently linked protein-DNA intermediate. | lld:pubmed |
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| pubmed-article:7556103 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7556103 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7556103 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7556103 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7556103 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:7556103 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7556103 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:7556103 | pubmed:issn | 0261-4189 | lld:pubmed |
| pubmed-article:7556103 | pubmed:author | pubmed-author:LiuJJ | lld:pubmed |
| pubmed-article:7556103 | pubmed:author | pubmed-author:LichterII | lld:pubmed |
| pubmed-article:7556103 | pubmed:author | pubmed-author:WuT CTC | lld:pubmed |
| pubmed-article:7556103 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7556103 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:7556103 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:7556103 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7556103 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7556103 | pubmed:pagination | 4599-608 | lld:pubmed |
| pubmed-article:7556103 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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