| pubmed-article:7554911 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7554911 | lifeskim:mentions | umls-concept:C0005532 | lld:lifeskim |
| pubmed-article:7554911 | lifeskim:mentions | umls-concept:C0040437 | lld:lifeskim |
| pubmed-article:7554911 | lifeskim:mentions | umls-concept:C0178499 | lld:lifeskim |
| pubmed-article:7554911 | lifeskim:mentions | umls-concept:C0185125 | lld:lifeskim |
| pubmed-article:7554911 | lifeskim:mentions | umls-concept:C1527178 | lld:lifeskim |
| pubmed-article:7554911 | pubmed:issue | 1-4 | lld:pubmed |
| pubmed-article:7554911 | pubmed:dateCreated | 1995-11-6 | lld:pubmed |
| pubmed-article:7554911 | pubmed:abstractText | The dentition and the alveolar process of each jaw develop simultaneously so that, by the time the crown is completed and eruption begins, the crown is enclosed in a crypt within alveolar bone. Thus, the eruption of a tooth to its functional position involves discretely localized, bilaterally symmetrical bone resorption to produce an eruption pathway and bone formation to fill in the space previously occupied by the crown and growing roots. Studies of crypt surfaces during eruption confirm this polarization of alveolar bone metabolism around a tooth with respect to both bone cells and mineralized surface topography. Experimental studies of tooth eruption have shown that the dental follicle, the dense connective tissue investment of the tooth, is necessary for eruption and that neither bone resorption nor bone formation occur without the adjacent part of the dental follicle. Early in eruption the coronal part of the follicle accumulates mononuclear cells which have cytochemical and ultrastructural features of osteoclasts and the apical part of the follicle, a site of intense cell proliferation, binds epidermal growth factor (EGF). The dental follicle contains a variety of proteins and the concentration of several change during eruption. Prominent among them are a reduction in matrix metalloproteinases and an increase in protoglycans as eruption proceeds. The contribution of these changes to those in cell proliferation, migration and differentiation during tooth eruption present experimental opportunities for developmental biologists. The rate-limiting factor of the earliest (intraosseous) stage of tooth eruption is bone resorption and eruption can be accelerated or retarded by the local delivery of factors which increase or decrease the activity of osteoclasts.(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:7554911 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7554911 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7554911 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7554911 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7554911 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7554911 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7554911 | pubmed:issn | 0300-8207 | lld:pubmed |
| pubmed-article:7554911 | pubmed:author | pubmed-author:MarksS CSCJr | lld:pubmed |
| pubmed-article:7554911 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7554911 | pubmed:volume | 32 | lld:pubmed |
| pubmed-article:7554911 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7554911 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7554911 | pubmed:pagination | 149-57 | lld:pubmed |
| pubmed-article:7554911 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7554911 | pubmed:meshHeading | pubmed-meshheading:7554911-... | lld:pubmed |
| pubmed-article:7554911 | pubmed:meshHeading | pubmed-meshheading:7554911-... | lld:pubmed |
| pubmed-article:7554911 | pubmed:meshHeading | pubmed-meshheading:7554911-... | lld:pubmed |
| pubmed-article:7554911 | pubmed:meshHeading | pubmed-meshheading:7554911-... | lld:pubmed |
| pubmed-article:7554911 | pubmed:meshHeading | pubmed-meshheading:7554911-... | lld:pubmed |
| pubmed-article:7554911 | pubmed:meshHeading | pubmed-meshheading:7554911-... | lld:pubmed |
| pubmed-article:7554911 | pubmed:meshHeading | pubmed-meshheading:7554911-... | lld:pubmed |
| pubmed-article:7554911 | pubmed:meshHeading | pubmed-meshheading:7554911-... | lld:pubmed |
| pubmed-article:7554911 | pubmed:meshHeading | pubmed-meshheading:7554911-... | lld:pubmed |
| pubmed-article:7554911 | pubmed:meshHeading | pubmed-meshheading:7554911-... | lld:pubmed |
| pubmed-article:7554911 | pubmed:meshHeading | pubmed-meshheading:7554911-... | lld:pubmed |
| pubmed-article:7554911 | pubmed:meshHeading | pubmed-meshheading:7554911-... | lld:pubmed |
| pubmed-article:7554911 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7554911 | pubmed:articleTitle | The basic and applied biology of tooth eruption. | lld:pubmed |
| pubmed-article:7554911 | pubmed:affiliation | Department of Cell Biology, University of Massachusetts Medical Center, Worcester 01655, USA. | lld:pubmed |
| pubmed-article:7554911 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7554911 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:7554911 | pubmed:publicationType | Review | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7554911 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7554911 | lld:pubmed |
