| pubmed-article:7542004 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7542004 | lifeskim:mentions | umls-concept:C0003316 | lld:lifeskim |
| pubmed-article:7542004 | lifeskim:mentions | umls-concept:C0004358 | lld:lifeskim |
| pubmed-article:7542004 | lifeskim:mentions | umls-concept:C0409998 | lld:lifeskim |
| pubmed-article:7542004 | lifeskim:mentions | umls-concept:C0006560 | lld:lifeskim |
| pubmed-article:7542004 | lifeskim:mentions | umls-concept:C0001347 | lld:lifeskim |
| pubmed-article:7542004 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:7542004 | pubmed:dateCreated | 1995-8-18 | lld:pubmed |
| pubmed-article:7542004 | pubmed:abstractText | Toxic oil syndrome (TOS) was caused by the consumption of rapeseed oil contaminated with derivatives of aniline. Many persons who survived the acute phase developed a puzzling, multi-year chronic disease considered to be inflammatory or autoimmune in nature. In attempting to characterize their autoantibodies, we found that 74% of TOS patients with chronic disease had IgG antibodies to C-reactive protein (CRP). This activity was detectable only when CRP was chemically or physically denatured and behaved like a previously described antibody produced by immunization with the CRP monomer. Significant antibody reactivities to other acute phase proteins, especially alpha 1-antitrypsin and fibrinogen (P < 0.025) and ceruloplasmin (P < 0.05) were also observed. IgG antibodies to cryptic epitopes in CRP and other major serum proteins that increase during the acute phase response may reflect an earlier toxin-mediated insult to the liver that included abnormal biosynthesis of and/or damage to acute phase proteins. | lld:pubmed |
| pubmed-article:7542004 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7542004 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7542004 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7542004 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7542004 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:7542004 | pubmed:issn | 0896-8411 | lld:pubmed |
| pubmed-article:7542004 | pubmed:author | pubmed-author:PicazoJ JJJ | lld:pubmed |
| pubmed-article:7542004 | pubmed:author | pubmed-author:Du ClosT WTW | lld:pubmed |
| pubmed-article:7542004 | pubmed:author | pubmed-author:RubinR LRL | lld:pubmed |
| pubmed-article:7542004 | pubmed:author | pubmed-author:BellS ASA | lld:pubmed |
| pubmed-article:7542004 | pubmed:author | pubmed-author:KhursigaraGG | lld:pubmed |
| pubmed-article:7542004 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7542004 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:7542004 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7542004 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7542004 | pubmed:pagination | 293-303 | lld:pubmed |
| pubmed-article:7542004 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7542004 | pubmed:meshHeading | pubmed-meshheading:7542004-... | lld:pubmed |
| pubmed-article:7542004 | pubmed:meshHeading | pubmed-meshheading:7542004-... | lld:pubmed |
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| pubmed-article:7542004 | pubmed:meshHeading | pubmed-meshheading:7542004-... | lld:pubmed |
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| pubmed-article:7542004 | pubmed:meshHeading | pubmed-meshheading:7542004-... | lld:pubmed |
| pubmed-article:7542004 | pubmed:meshHeading | pubmed-meshheading:7542004-... | lld:pubmed |
| pubmed-article:7542004 | pubmed:meshHeading | pubmed-meshheading:7542004-... | lld:pubmed |
| pubmed-article:7542004 | pubmed:meshHeading | pubmed-meshheading:7542004-... | lld:pubmed |
| pubmed-article:7542004 | pubmed:meshHeading | pubmed-meshheading:7542004-... | lld:pubmed |
| pubmed-article:7542004 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7542004 | pubmed:articleTitle | Autoantibodies to cryptic epitopes of C-reactive protein and other acute phase proteins in the toxic oil syndrome. | lld:pubmed |
| pubmed-article:7542004 | pubmed:affiliation | W.M. Keck Autoimmune Disease Center, Department of Molecular and Experimental Medicine, Scripps Research Institute, La Jolla, California 92037, USA. | lld:pubmed |
| pubmed-article:7542004 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7542004 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:7542004 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7542004 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7542004 | lld:pubmed |
