| pubmed-article:7532548 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7532548 | lifeskim:mentions | umls-concept:C0014644 | lld:lifeskim |
| pubmed-article:7532548 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:7532548 | lifeskim:mentions | umls-concept:C0206188 | lld:lifeskim |
| pubmed-article:7532548 | lifeskim:mentions | umls-concept:C0205307 | lld:lifeskim |
| pubmed-article:7532548 | lifeskim:mentions | umls-concept:C0376315 | lld:lifeskim |
| pubmed-article:7532548 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:7532548 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:7532548 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:7532548 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:7532548 | pubmed:dateCreated | 1995-3-28 | lld:pubmed |
| pubmed-article:7532548 | pubmed:abstractText | We have developed a PCR assay that can detect a single Epstein-Barr virus (EBV) genome in the presence of 10(6) uninfected cells. Using this assay, we demonstrate that EBV persists, in the peripheral blood of all seropositive individuals tested, in CD19+, CD23-, and CD80 (B7)- B cells. We further show that the virus in these cells is latent, but readily reactivated to produce infectious immortalizing virus; therefore, these cells represent a true site of latent persistence. EBV was not significantly detected in monocytes or T cells. The frequency of infected cells in nine healthy donors varied from 23 to 625 per 10(7) B cells, but was relatively stable for each individual over the course of 2 years. We conclude that the EBV-infected cells in vivo are B cells with a nonactivated phenotype. This represents a novel form of latency in normal B cells. | lld:pubmed |
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| pubmed-article:7532548 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:7532548 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:7532548 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7532548 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:7532548 | pubmed:issn | 0092-8674 | lld:pubmed |
| pubmed-article:7532548 | pubmed:author | pubmed-author:LamK MKM | lld:pubmed |
| pubmed-article:7532548 | pubmed:author | pubmed-author:YanoJJ | lld:pubmed |
| pubmed-article:7532548 | pubmed:author | pubmed-author:CrawfordD HDH | lld:pubmed |
| pubmed-article:7532548 | pubmed:author | pubmed-author:Thorley-Lawso... | lld:pubmed |
| pubmed-article:7532548 | pubmed:author | pubmed-author:MiyashitaE... | lld:pubmed |
| pubmed-article:7532548 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7532548 | pubmed:day | 24 | lld:pubmed |
| pubmed-article:7532548 | pubmed:volume | 80 | lld:pubmed |
| pubmed-article:7532548 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7532548 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7532548 | pubmed:pagination | 593-601 | lld:pubmed |
| pubmed-article:7532548 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:7532548 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7532548 | pubmed:articleTitle | A novel form of Epstein-Barr virus latency in normal B cells in vivo. | lld:pubmed |
| pubmed-article:7532548 | pubmed:affiliation | Department of Pathology, Tufts University School of Medicine, Boston, Massachusetts 02111. | lld:pubmed |
| pubmed-article:7532548 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7532548 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:7532548 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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