| pubmed-article:7530829 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7530829 | lifeskim:mentions | umls-concept:C0080298 | lld:lifeskim |
| pubmed-article:7530829 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:7530829 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:7530829 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:7530829 | lifeskim:mentions | umls-concept:C1510411 | lld:lifeskim |
| pubmed-article:7530829 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:7530829 | pubmed:dateCreated | 1995-2-27 | lld:pubmed |
| pubmed-article:7530829 | pubmed:abstractText | Previous studies in which chicken and human c-Src were overexpressed in chicken and rodent cells have indicated that overexpression of wild-type c-Src can not induce complete neoplastic transformation. However, studies with v-Src mutants have demonstrated that species-specific differences can play a significant role in transforming activity. Here we show that, in contrast to chicken c-Src, overexpressed mouse c-Src can induce significant anchorage-independent growth and tumorigenicity when transfected into NIH3T3 mouse cells. The biochemical cause for this difference is unknown. In particular, the protein-tyrosine kinase activities of chicken and mouse c-Src appear to be similar. This result is consistent with the hypothesis that v-Src-induced transformation results from perturbation of signalling pathways modulated by c-Src and highlights the need for caution in controlling for potential species-specific differences in studies of c-Src function. | lld:pubmed |
| pubmed-article:7530829 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7530829 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7530829 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7530829 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7530829 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7530829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7530829 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7530829 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:7530829 | pubmed:issn | 0950-9232 | lld:pubmed |
| pubmed-article:7530829 | pubmed:author | pubmed-author:KARS BSB | lld:pubmed |
| pubmed-article:7530829 | pubmed:author | pubmed-author:ShenoySS | lld:pubmed |
| pubmed-article:7530829 | pubmed:author | pubmed-author:ShallowayDD | lld:pubmed |
| pubmed-article:7530829 | pubmed:author | pubmed-author:GalitskiTT | lld:pubmed |
| pubmed-article:7530829 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7530829 | pubmed:day | 19 | lld:pubmed |
| pubmed-article:7530829 | pubmed:volume | 10 | lld:pubmed |
| pubmed-article:7530829 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7530829 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7530829 | pubmed:pagination | 401-5 | lld:pubmed |
| pubmed-article:7530829 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:7530829 | pubmed:meshHeading | pubmed-meshheading:7530829-... | lld:pubmed |
| pubmed-article:7530829 | pubmed:meshHeading | pubmed-meshheading:7530829-... | lld:pubmed |
| pubmed-article:7530829 | pubmed:meshHeading | pubmed-meshheading:7530829-... | lld:pubmed |
| pubmed-article:7530829 | pubmed:meshHeading | pubmed-meshheading:7530829-... | lld:pubmed |
| pubmed-article:7530829 | pubmed:meshHeading | pubmed-meshheading:7530829-... | lld:pubmed |
| pubmed-article:7530829 | pubmed:meshHeading | pubmed-meshheading:7530829-... | lld:pubmed |
| pubmed-article:7530829 | pubmed:meshHeading | pubmed-meshheading:7530829-... | lld:pubmed |
| pubmed-article:7530829 | pubmed:meshHeading | pubmed-meshheading:7530829-... | lld:pubmed |
| pubmed-article:7530829 | pubmed:meshHeading | pubmed-meshheading:7530829-... | lld:pubmed |
| pubmed-article:7530829 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7530829 | pubmed:articleTitle | Transformation of mouse cells by wild-type mouse c-Src. | lld:pubmed |
| pubmed-article:7530829 | pubmed:affiliation | Section of Biochemistry, Molecular and Cell Biology, Cornell University, Ithaca, New York 14853. | lld:pubmed |
| pubmed-article:7530829 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7530829 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| entrez-gene:20779 | entrezgene:pubmed | pubmed-article:7530829 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7530829 | lld:pubmed |
