| pubmed-article:7500988 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7500988 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:7500988 | lifeskim:mentions | umls-concept:C0007097 | lld:lifeskim |
| pubmed-article:7500988 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
| pubmed-article:7500988 | lifeskim:mentions | umls-concept:C1257806 | lld:lifeskim |
| pubmed-article:7500988 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:7500988 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:7500988 | pubmed:dateCreated | 1996-1-18 | lld:pubmed |
| pubmed-article:7500988 | pubmed:abstractText | The Gorlin syndrome, or naevoid basal-cell carcinoma syndrome (NBCS) is an autosomal dominant disease. It has been suspected for long that this cancer prone disease (multiple basal-cell carcinomas; other malignant or benign proliferations) is a chromosome instability syndrome. We previously reported a lengthening in the cell cycle of lymphocytes from two patients with NBCS. With a larger sample (n = 7), we confirm this disease to be a chromosome instability syndrome, although clearly, expression of this characteristic can vary between patients: (1) spontaneous chromatid breaks occurred more often in a subset of the patients; (2) spontaneous micronuclei were found more frequently in NBCS than in the controls; (3) we confirm the cell cycle to be affected in this disease. As these results were obtained on lymphocytes--a cell lineage not affected in NBCS manifestations--the chromosome instability we found would appear to be part of the general condition of this syndrome. | lld:pubmed |
| pubmed-article:7500988 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7500988 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7500988 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7500988 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7500988 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:7500988 | pubmed:issn | 0027-5107 | lld:pubmed |
| pubmed-article:7500988 | pubmed:author | pubmed-author:BonnetblancJ... | lld:pubmed |
| pubmed-article:7500988 | pubmed:author | pubmed-author:SavageJ RJR | lld:pubmed |
| pubmed-article:7500988 | pubmed:author | pubmed-author:TanzerJJ | lld:pubmed |
| pubmed-article:7500988 | pubmed:author | pubmed-author:BabinPP | lld:pubmed |
| pubmed-article:7500988 | pubmed:author | pubmed-author:LarrègueMM | lld:pubmed |
| pubmed-article:7500988 | pubmed:author | pubmed-author:VaillantLL | lld:pubmed |
| pubmed-article:7500988 | pubmed:author | pubmed-author:HuretJ LJL | lld:pubmed |
| pubmed-article:7500988 | pubmed:author | pubmed-author:PapworthDD | lld:pubmed |
| pubmed-article:7500988 | pubmed:author | pubmed-author:Shafei-Benais... | lld:pubmed |
| pubmed-article:7500988 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7500988 | pubmed:volume | 332 | lld:pubmed |
| pubmed-article:7500988 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7500988 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7500988 | pubmed:pagination | 27-32 | lld:pubmed |
| pubmed-article:7500988 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7500988 | pubmed:meshHeading | pubmed-meshheading:7500988-... | lld:pubmed |
| pubmed-article:7500988 | pubmed:meshHeading | pubmed-meshheading:7500988-... | lld:pubmed |
| pubmed-article:7500988 | pubmed:meshHeading | pubmed-meshheading:7500988-... | lld:pubmed |
| pubmed-article:7500988 | pubmed:meshHeading | pubmed-meshheading:7500988-... | lld:pubmed |
| pubmed-article:7500988 | pubmed:meshHeading | pubmed-meshheading:7500988-... | lld:pubmed |
| pubmed-article:7500988 | pubmed:meshHeading | pubmed-meshheading:7500988-... | lld:pubmed |
| pubmed-article:7500988 | pubmed:meshHeading | pubmed-meshheading:7500988-... | lld:pubmed |
| pubmed-article:7500988 | pubmed:meshHeading | pubmed-meshheading:7500988-... | lld:pubmed |
| pubmed-article:7500988 | pubmed:meshHeading | pubmed-meshheading:7500988-... | lld:pubmed |
| pubmed-article:7500988 | pubmed:meshHeading | pubmed-meshheading:7500988-... | lld:pubmed |
| pubmed-article:7500988 | pubmed:meshHeading | pubmed-meshheading:7500988-... | lld:pubmed |
| pubmed-article:7500988 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7500988 | pubmed:articleTitle | Evidence of chromosomal instability in the lymphocytes of Gorlin basal-cell carcinoma patients. | lld:pubmed |
| pubmed-article:7500988 | pubmed:affiliation | Cytogénétique, Laboratoire Hématologie, CHU la Milètrie, Poitiers, France. | lld:pubmed |
| pubmed-article:7500988 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7500988 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7500988 | lld:pubmed |
