| pubmed-article:7483689 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7483689 | lifeskim:mentions | umls-concept:C0032708 | lld:lifeskim |
| pubmed-article:7483689 | lifeskim:mentions | umls-concept:C0020435 | lld:lifeskim |
| pubmed-article:7483689 | lifeskim:mentions | umls-concept:C0348026 | lld:lifeskim |
| pubmed-article:7483689 | pubmed:dateCreated | 1995-12-14 | lld:pubmed |
| pubmed-article:7483689 | pubmed:abstractText | Secondary porphyrinopathias were investigated in hereditary hyperbilirubinemias of the types Dubin-Johnson syndrome (DJS), Rotor's syndrome (RS), Gilbert's syndrome (GS) and compared with the findings in alcohol-induced cholestasis. The determination of urinary coproporphyrin excretion including its isomer I and III relation allows to diagnose and differentiate DJS from the other two forms of hereditary hyperbilirubinemias. An isomer I proportion of > 80% (normal < 32%) in association with a normal coproporphyrin excretion is pathognomonic for DJS. An increased coproporphyrinuria with about 70% isomer I is found in RS; a normal urinary coproporphyrin excretion combined with an isomer I increase of about 50-70% indicates the frequent GS. Alcohol-related cholestasis reveals a distinct pathologic coproporphyrinuria and elevated isomer I proportions between 37-67%. Due to the overlapping of isomer alterations in DJS-gene carriers, patients with GS and patients with exogenous toxically-induced cholestasis, additional diagnostic criteria are required to clarify the porphyrinopathia in its clinical context. | lld:pubmed |
| pubmed-article:7483689 | pubmed:language | ger | lld:pubmed |
| pubmed-article:7483689 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7483689 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7483689 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7483689 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7483689 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:7483689 | pubmed:issn | 0044-2771 | lld:pubmed |
| pubmed-article:7483689 | pubmed:author | pubmed-author:FrankMM | lld:pubmed |
| pubmed-article:7483689 | pubmed:author | pubmed-author:DossM OMO | lld:pubmed |
| pubmed-article:7483689 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7483689 | pubmed:volume | 31 Suppl 2 | lld:pubmed |
| pubmed-article:7483689 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7483689 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7483689 | pubmed:pagination | 111-3 | lld:pubmed |
| pubmed-article:7483689 | pubmed:dateRevised | 2009-11-11 | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:meshHeading | pubmed-meshheading:7483689-... | lld:pubmed |
| pubmed-article:7483689 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:7483689 | pubmed:articleTitle | [Diagnostic porphyrinopathies in hereditary hyperbilirubinemia]. | lld:pubmed |
| pubmed-article:7483689 | pubmed:affiliation | Abteilung für Gastroenterologie und Stoffwechsel, Universitätsklinik Marburg. | lld:pubmed |
| pubmed-article:7483689 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7483689 | pubmed:publicationType | English Abstract | lld:pubmed |
| pubmed-article:7483689 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
