| pubmed-article:7462233 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7462233 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:7462233 | lifeskim:mentions | umls-concept:C0001492 | lld:lifeskim |
| pubmed-article:7462233 | lifeskim:mentions | umls-concept:C0178702 | lld:lifeskim |
| pubmed-article:7462233 | lifeskim:mentions | umls-concept:C0883208 | lld:lifeskim |
| pubmed-article:7462233 | lifeskim:mentions | umls-concept:C1948027 | lld:lifeskim |
| pubmed-article:7462233 | lifeskim:mentions | umls-concept:C0205224 | lld:lifeskim |
| pubmed-article:7462233 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:7462233 | pubmed:dateCreated | 1981-4-24 | lld:pubmed |
| pubmed-article:7462233 | pubmed:abstractText | Epinephrine or prostaglandin E1 pretreatment of intact S-49 lymphoma cells specifically desensitized adenylate cyclase activity. Cholate extracts of membranes from these desensitized cells showed no difference from controls in their reconstitution of hormone-stimulated adenylate cyclase activity in the adenylate cyclase-deficient variant (cyc-) of the lymphoma cell line. Adenylate cyclase in the cyc- variant was also specifically desensitized by epinephrine in prostaglandin E1. The desensitization was assessed by reconstituting the cyc- adenylate cyclase with cholate extracts of the wild type lymphoma cells. Since the cyc- has been shown to lack the coupling or G/F proteins of the adenylate cyclase complex, and these proteins are restored by cholate extracts from wild type cells, we conclude that the G/F proteins are not altered or necessary for specific desensitization of the lymphoma cell lines. | lld:pubmed |
| pubmed-article:7462233 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7462233 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7462233 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7462233 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7462233 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7462233 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7462233 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:7462233 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7462233 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7462233 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:7462233 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:7462233 | pubmed:author | pubmed-author:ClarkR BRB | lld:pubmed |
| pubmed-article:7462233 | pubmed:author | pubmed-author:GreenD ADA | lld:pubmed |
| pubmed-article:7462233 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7462233 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:7462233 | pubmed:volume | 256 | lld:pubmed |
| pubmed-article:7462233 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7462233 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7462233 | pubmed:pagination | 2105-8 | lld:pubmed |
| pubmed-article:7462233 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7462233 | pubmed:meshHeading | pubmed-meshheading:7462233-... | lld:pubmed |
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| pubmed-article:7462233 | pubmed:meshHeading | pubmed-meshheading:7462233-... | lld:pubmed |
| pubmed-article:7462233 | pubmed:meshHeading | pubmed-meshheading:7462233-... | lld:pubmed |
| pubmed-article:7462233 | pubmed:meshHeading | pubmed-meshheading:7462233-... | lld:pubmed |
| pubmed-article:7462233 | pubmed:meshHeading | pubmed-meshheading:7462233-... | lld:pubmed |
| pubmed-article:7462233 | pubmed:meshHeading | pubmed-meshheading:7462233-... | lld:pubmed |
| pubmed-article:7462233 | pubmed:meshHeading | pubmed-meshheading:7462233-... | lld:pubmed |
| pubmed-article:7462233 | pubmed:meshHeading | pubmed-meshheading:7462233-... | lld:pubmed |
| pubmed-article:7462233 | pubmed:year | 1981 | lld:pubmed |
| pubmed-article:7462233 | pubmed:articleTitle | Adenylate cyclase coupling proteins are not essential for agonist-specific desensitization of lymphoma cells. | lld:pubmed |
| pubmed-article:7462233 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7462233 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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