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pubmed-article:7390386pubmed:abstractTextA total of 98 patients selected and classified into type IIa and IIb hyperlipoproteinemia according to Fredrickson and Lees (1965) were pre-treated for 6 months with a commercially available combination product (containing clofibrate and nicotinic acid). After randomization this pre-treatment was followed by a further 8 week-treatment with the comparison product (group I = 49 patients) or by a change-over to Lipo-Merz retard (group II = 49 patients). Lipo-Merz retard was administered in a dosage of one capsule/day, the combination product in a dosage of one capsule three times daily. In group I the serum cholesterol and serum triglyceride values achieved by the pre-treatment could be lowered by an average of 4%. In group II the reductions were 4% and 6%, respectively. Toleration was good in both groups.lld:pubmed
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pubmed-article:7390386pubmed:articleTitle[Therapy of lipoproteinemia. Comparison between Lipo-Merz retard and a commercial combination drug].lld:pubmed
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