| pubmed-article:7371974 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7371974 | lifeskim:mentions | umls-concept:C0567416 | lld:lifeskim |
| pubmed-article:7371974 | lifeskim:mentions | umls-concept:C0040123 | lld:lifeskim |
| pubmed-article:7371974 | lifeskim:mentions | umls-concept:C0030011 | lld:lifeskim |
| pubmed-article:7371974 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:7371974 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:7371974 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:7371974 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:7371974 | pubmed:dateCreated | 1980-7-22 | lld:pubmed |
| pubmed-article:7371974 | pubmed:abstractText | Previous electron-microscopical studies from this laboratory have shown that the thyroglobulin molecule can occur in two different conformations, one ovoid and the other cylindrical. Ovoid molecules are characteristic of well-iodinated thyroglobulin whereas cylindrical molecules are found after low-iodine diet or blocking of iodination. The present study was performed in order to elucidate the possible relation between the molecule conformation and the peroxidase-catalyzed reactions that occur in the thyroid in connection with hormone synthesis. Cylindrical thyroglobulin molecules (from PTU-exposed thyroids) were incubated in different media and the proportion of cylindrical and ovoid molecules after incubation was estimated in electron micrographs. It was found that incubation with glucose-glucose oxidase caused an extensive conversion of cylindrical molecules into ovoid molecules. Peroxidase and/or iodide were not necessary for this change of conformation. It is suggested that this in vitro molecule transformation was the result of an oxidation reaction. | lld:pubmed |
| pubmed-article:7371974 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7371974 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7371974 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7371974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7371974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7371974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7371974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7371974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7371974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7371974 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7371974 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:7371974 | pubmed:issn | 0303-7207 | lld:pubmed |
| pubmed-article:7371974 | pubmed:author | pubmed-author:BergGG | lld:pubmed |
| pubmed-article:7371974 | pubmed:author | pubmed-author:EkholmRR | lld:pubmed |
| pubmed-article:7371974 | pubmed:author | pubmed-author:BjörkmanUU | lld:pubmed |
| pubmed-article:7371974 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7371974 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:7371974 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7371974 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7371974 | pubmed:pagination | 139-44 | lld:pubmed |
| pubmed-article:7371974 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:7371974 | pubmed:meshHeading | pubmed-meshheading:7371974-... | lld:pubmed |
| pubmed-article:7371974 | pubmed:meshHeading | pubmed-meshheading:7371974-... | lld:pubmed |
| pubmed-article:7371974 | pubmed:meshHeading | pubmed-meshheading:7371974-... | lld:pubmed |
| pubmed-article:7371974 | pubmed:year | 1980 | lld:pubmed |
| pubmed-article:7371974 | pubmed:articleTitle | Conformational change of the thyroglobulin molecule induced by oxidation in vitro. | lld:pubmed |
| pubmed-article:7371974 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7371974 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7371974 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7371974 | lld:pubmed |
