Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:7328582rdf:typepubmed:Citationlld:pubmed
pubmed-article:7328582lifeskim:mentionsumls-concept:C0040845lld:lifeskim
pubmed-article:7328582lifeskim:mentionsumls-concept:C0441655lld:lifeskim
pubmed-article:7328582lifeskim:mentionsumls-concept:C0220781lld:lifeskim
pubmed-article:7328582lifeskim:mentionsumls-concept:C1883254lld:lifeskim
pubmed-article:7328582lifeskim:mentionsumls-concept:C0392747lld:lifeskim
pubmed-article:7328582lifeskim:mentionsumls-concept:C0205464lld:lifeskim
pubmed-article:7328582lifeskim:mentionsumls-concept:C0243071lld:lifeskim
pubmed-article:7328582lifeskim:mentionsumls-concept:C1260969lld:lifeskim
pubmed-article:7328582lifeskim:mentionsumls-concept:C1554963lld:lifeskim
pubmed-article:7328582pubmed:issue10lld:pubmed
pubmed-article:7328582pubmed:dateCreated1982-4-20lld:pubmed
pubmed-article:7328582pubmed:abstractTextAnalogues of retinoic acid that have their major modifications in the 5,6 double bond and 4-methylene group regions of the beta-cyclogeranylidene ring have been synthesized as potential agents for the treatment and prevention of epithelial cancer. These modifications were intended to reduce retinoid toxicity by lowering the effective treatment dose because the major metabolic deactivation pathway would be inhibited. Ethyl (E)-3,7-dimethyl-9-(exo-2-bicyclo[2.2.1]-heptyl)-2,4,6,8-nonatetraenoate (7), ethyl (E)-3,7-dimethyl-9-(2,2,6-trimethylbicyclo[4.1.0]hept-1-yl)-2,4,6,8-nonatetraen oate (18), (E)-1-(4-carbethoxyphenyl)-2-methyl-4-(2,2,6-trimethylbicyclo[4.1.0]hept-1-yl)- 1,3-butadiene (28), (E)-retinoic acid-4,4,18,18,18-d5 (39), and ethyl (E)-3,7-dimethyl-9-(3,3-ethano-2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate (47) displayed moderate to excellent activity in an assay for the inhibition of tumor promoter-induced mouse epidermal ornithine decarboxylase.lld:pubmed
pubmed-article:7328582pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7328582pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7328582pubmed:languageenglld:pubmed
pubmed-article:7328582pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7328582pubmed:citationSubsetIMlld:pubmed
pubmed-article:7328582pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7328582pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7328582pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7328582pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7328582pubmed:statusMEDLINElld:pubmed
pubmed-article:7328582pubmed:monthOctlld:pubmed
pubmed-article:7328582pubmed:issn0022-2623lld:pubmed
pubmed-article:7328582pubmed:authorpubmed-author:ChaoW RWRlld:pubmed
pubmed-article:7328582pubmed:authorpubmed-author:DawsonM IMIlld:pubmed
pubmed-article:7328582pubmed:authorpubmed-author:ChanR LRLlld:pubmed
pubmed-article:7328582pubmed:authorpubmed-author:HobbsP DPDlld:pubmed
pubmed-article:7328582pubmed:issnTypePrintlld:pubmed
pubmed-article:7328582pubmed:volume24lld:pubmed
pubmed-article:7328582pubmed:ownerNLMlld:pubmed
pubmed-article:7328582pubmed:authorsCompleteYlld:pubmed
pubmed-article:7328582pubmed:pagination1214-23lld:pubmed
pubmed-article:7328582pubmed:dateRevised2007-11-14lld:pubmed
pubmed-article:7328582pubmed:meshHeadingpubmed-meshheading:7328582-...lld:pubmed
pubmed-article:7328582pubmed:meshHeadingpubmed-meshheading:7328582-...lld:pubmed
pubmed-article:7328582pubmed:meshHeadingpubmed-meshheading:7328582-...lld:pubmed
pubmed-article:7328582pubmed:meshHeadingpubmed-meshheading:7328582-...lld:pubmed
pubmed-article:7328582pubmed:meshHeadingpubmed-meshheading:7328582-...lld:pubmed
pubmed-article:7328582pubmed:meshHeadingpubmed-meshheading:7328582-...lld:pubmed
pubmed-article:7328582pubmed:meshHeadingpubmed-meshheading:7328582-...lld:pubmed
pubmed-article:7328582pubmed:meshHeadingpubmed-meshheading:7328582-...lld:pubmed
pubmed-article:7328582pubmed:meshHeadingpubmed-meshheading:7328582-...lld:pubmed
pubmed-article:7328582pubmed:year1981lld:pubmed
pubmed-article:7328582pubmed:articleTitleRetinoic acid analogues with ring modifications. Synthesis and pharmacological activity.lld:pubmed
pubmed-article:7328582pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:7328582pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
http://linkedlifedata.com/r...http://linkedlifedata.com/r...pubmed-article:7328582lld:chembl
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7328582lld:pubmed