pubmed-article:7275833 | pubmed:abstractText | The four amino groups of fortimicin B(4) could be differentiated from each other and 2'-N-benzyloxycarbonyl-, 2',6'-di-N-benzyloxycarbonyl-, 2'-N-tert-butoxycarbonyl-, 6'-N-tert-butoxycarbonyl- and 2',6'-di-N-tert-butoxycarbonyl-fortimicin B (7, 8, 16, 18, 17) were prepared from 4. From these fortimicin B derivatives, selectively protected fortimicin A derivatives 13, 15, 21, 22 and 25 were prepared by combination of procedures of benzyloxycarbonylation or tert-butoxycarbonylation, 4-N-glycylation. | lld:pubmed |