| pubmed-article:7251659 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7251659 | lifeskim:mentions | umls-concept:C1511934 | lld:lifeskim |
| pubmed-article:7251659 | lifeskim:mentions | umls-concept:C0815000 | lld:lifeskim |
| pubmed-article:7251659 | lifeskim:mentions | umls-concept:C0041348 | lld:lifeskim |
| pubmed-article:7251659 | lifeskim:mentions | umls-concept:C1509144 | lld:lifeskim |
| pubmed-article:7251659 | lifeskim:mentions | umls-concept:C0337051 | lld:lifeskim |
| pubmed-article:7251659 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:7251659 | pubmed:dateCreated | 1981-9-25 | lld:pubmed |
| pubmed-article:7251659 | pubmed:abstractText | The distribution of tubulin in soluble, reversibly stabilized (assembled) and insoluble forms has been determined in neuroblastoma cells undergoing microtubule-dependent neurite elongation. Procedures were developed to obtain reproducible tubulin fractions and to assay total tubulin. Radioimmunoassays showed that both differentiated and nondifferentiated cell contained approximately 4 pg of tubulin per cell, of which 3-10% was in an insoluble, particulate form. The amount of tubulin assembled in differentiated cells was four to five times greater than in nondifferentiated cells, constituting 48-63% and 11-16% of the total tubulin pool in the respective cell types. Calculation of the concentration of soluble tubulin indifferentiated cells (approximately 0.8 mg/ml) and nondifferentiated cells (approximately 1.6 mg/ml) indicates that a critical concentration of subunits probably does not limit the induction of microtubule formation during neurite elongation. | lld:pubmed |
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| pubmed-article:7251659 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:7251659 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:7251659 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7251659 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:7251659 | pubmed:issn | 0021-9525 | lld:pubmed |
| pubmed-article:7251659 | pubmed:author | pubmed-author:OlmstedJ BJB | lld:pubmed |
| pubmed-article:7251659 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7251659 | pubmed:volume | 89 | lld:pubmed |
| pubmed-article:7251659 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7251659 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7251659 | pubmed:pagination | 418-23 | lld:pubmed |
| pubmed-article:7251659 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:7251659 | pubmed:year | 1981 | lld:pubmed |
| pubmed-article:7251659 | pubmed:articleTitle | Tubulin pools in differentiating neuroblastoma cells. | lld:pubmed |
| pubmed-article:7251659 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7251659 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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