| pubmed-article:7208146 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7208146 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:7208146 | lifeskim:mentions | umls-concept:C0032105 | lld:lifeskim |
| pubmed-article:7208146 | lifeskim:mentions | umls-concept:C0520572 | lld:lifeskim |
| pubmed-article:7208146 | lifeskim:mentions | umls-concept:C0597619 | lld:lifeskim |
| pubmed-article:7208146 | lifeskim:mentions | umls-concept:C2673735 | lld:lifeskim |
| pubmed-article:7208146 | lifeskim:mentions | umls-concept:C1291208 | lld:lifeskim |
| pubmed-article:7208146 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:7208146 | pubmed:dateCreated | 1981-5-21 | lld:pubmed |
| pubmed-article:7208146 | pubmed:abstractText | Metabolic observations during early stages of hyperammonemia in two infants with ornithine transcarbamylase deficiency suggest that plasma alpha-ketoglutarate concentration ([alpha-KG]) becomes subnormal before the development of hyperammonemic coma. In one case, plasma [NH4+] remained normal until 40 days of age when it rose to 58 microM. However, this hyperammonemia was preceded by a fall in plasma [alpha-KG] to 15 microM at 27 days of age. It was only after severe hyperammonemia was established at 50 days of age that coma supervened. In the second case, plasma [alpha-KG] became subnormal (14 microM) 8 days before the rise in plasma ammonium concentration [NH4+] (52 microM) and 14 days before the onset of hyperammonemic coma. In eight patients with urea cycle enzymopathies, there was a highly significant (P less than 0.01) negative linear correlation between [NH4+] and [alpha-KG]. In patients with portal-systemic encephalopathy, there was a similar relationship between [NH4+] and [alpha-KG], although the absolute [alpha-KG] levels in these patients were normal (23 +/- 4 microM) while the patients were hyperammonemic (88 +/- 25 microM). | lld:pubmed |
| pubmed-article:7208146 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7208146 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7208146 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7208146 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7208146 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7208146 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7208146 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7208146 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7208146 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7208146 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7208146 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7208146 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7208146 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7208146 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:7208146 | pubmed:issn | 0031-3998 | lld:pubmed |
| pubmed-article:7208146 | pubmed:author | pubmed-author:WalserMM | lld:pubmed |
| pubmed-article:7208146 | pubmed:author | pubmed-author:BrusilowS WSW | lld:pubmed |
| pubmed-article:7208146 | pubmed:author | pubmed-author:BatshawM LML | lld:pubmed |
| pubmed-article:7208146 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7208146 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:7208146 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7208146 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7208146 | pubmed:pagination | 1316-9 | lld:pubmed |
| pubmed-article:7208146 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:7208146 | pubmed:meshHeading | pubmed-meshheading:7208146-... | lld:pubmed |
| pubmed-article:7208146 | pubmed:year | 1980 | lld:pubmed |
| pubmed-article:7208146 | pubmed:articleTitle | Plasma alpha-ketoglutarate in urea cycle enzymopathies and its role as a harbinger of hyperammonemic coma. | lld:pubmed |
| pubmed-article:7208146 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7208146 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:7208146 | pubmed:publicationType | Case Reports | lld:pubmed |
