pubmed-article:7203972 | pubmed:abstractText | The morphogenesis of vaccinia virus was studied during its synthesis in HeLa cells. Freeze-etching electron microscopy demonstrated intramembrane granules attached to convex faces, a granule-free area characterized by eccentric location and smooth appearance, and an eccentric nucleoid structure occasionally associated with a membranous structure. It is postulated that the granule-free area may be a precursor of the nucleoid envelope. | lld:pubmed |