| pubmed-article:7198634 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7198634 | lifeskim:mentions | umls-concept:C1566558 | lld:lifeskim |
| pubmed-article:7198634 | lifeskim:mentions | umls-concept:C0007625 | lld:lifeskim |
| pubmed-article:7198634 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:7198634 | lifeskim:mentions | umls-concept:C0008562 | lld:lifeskim |
| pubmed-article:7198634 | lifeskim:mentions | umls-concept:C0055075 | lld:lifeskim |
| pubmed-article:7198634 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:7198634 | lifeskim:mentions | umls-concept:C1524063 | lld:lifeskim |
| pubmed-article:7198634 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:7198634 | pubmed:dateCreated | 1982-3-22 | lld:pubmed |
| pubmed-article:7198634 | pubmed:abstractText | A new cepham metabolite has been isolated from the filtered broth of Cephalosporium acremonium by high performance liquid chromatography (HPLC) and identified as 7 beta-(5-D-amino-adipamido)-3 beta-hydroxy-3 alpha-methyl-cepham-4 alpha-carboxylic acid (I). Pure penicillin N was prepared using HPLC in the analytical mode. When I was added in place of penicillin N as substrate for the cell-free biosynthetic of cephalosporin, no formation of deacetoxycephalosporin C (II) was observed. A synthetic cepham derivative, 7 beta-(5-D-aminoadipamido)-3-exomethylene-cepham-4 alpha-carboxylic acid (III) was also tested in the cell-free system as a possible intermediate. The compound III was shown to be an inhibitor of the ring expansion enzyme that converts penicillin N to deacetoxycephalosporin C. | lld:pubmed |
| pubmed-article:7198634 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7198634 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7198634 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7198634 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7198634 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7198634 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7198634 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7198634 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7198634 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:7198634 | pubmed:issn | 0021-8820 | lld:pubmed |
| pubmed-article:7198634 | pubmed:author | pubmed-author:ElzeyT KTK | lld:pubmed |
| pubmed-article:7198634 | pubmed:author | pubmed-author:MillerR DRD | lld:pubmed |
| pubmed-article:7198634 | pubmed:author | pubmed-author:QueenerS WSW | lld:pubmed |
| pubmed-article:7198634 | pubmed:author | pubmed-author:KukoljaSS | lld:pubmed |
| pubmed-article:7198634 | pubmed:author | pubmed-author:NeussNN | lld:pubmed |
| pubmed-article:7198634 | pubmed:author | pubmed-author:HuckstepL LLL | lld:pubmed |
| pubmed-article:7198634 | pubmed:author | pubmed-author:LawrenceS MSM | lld:pubmed |
| pubmed-article:7198634 | pubmed:author | pubmed-author:SpryD ODO | lld:pubmed |
| pubmed-article:7198634 | pubmed:author | pubmed-author:McDermottJ... | lld:pubmed |
| pubmed-article:7198634 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7198634 | pubmed:volume | 34 | lld:pubmed |
| pubmed-article:7198634 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7198634 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7198634 | pubmed:pagination | 984-93 | lld:pubmed |
| pubmed-article:7198634 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
| pubmed-article:7198634 | pubmed:meshHeading | pubmed-meshheading:7198634-... | lld:pubmed |
| pubmed-article:7198634 | pubmed:meshHeading | pubmed-meshheading:7198634-... | lld:pubmed |
| pubmed-article:7198634 | pubmed:meshHeading | pubmed-meshheading:7198634-... | lld:pubmed |
| pubmed-article:7198634 | pubmed:meshHeading | pubmed-meshheading:7198634-... | lld:pubmed |
| pubmed-article:7198634 | pubmed:meshHeading | pubmed-meshheading:7198634-... | lld:pubmed |
| pubmed-article:7198634 | pubmed:meshHeading | pubmed-meshheading:7198634-... | lld:pubmed |
| pubmed-article:7198634 | pubmed:year | 1981 | lld:pubmed |
| pubmed-article:7198634 | pubmed:articleTitle | High performance liquid chromatography (HPLC) of natural products. IV. The use of HPLC in biosynthetic studies of cephalosporin C in the cell-free system. | lld:pubmed |
| pubmed-article:7198634 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7198634 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7198634 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7198634 | lld:pubmed |
