pubmed-article:708487 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:708487 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
pubmed-article:708487 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:708487 | lifeskim:mentions | umls-concept:C0342892 | lld:lifeskim |
pubmed-article:708487 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
pubmed-article:708487 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:708487 | pubmed:dateCreated | 1978-12-20 | lld:pubmed |
pubmed-article:708487 | pubmed:abstractText | The aim of this study was to examine in detail the lipid and apoprotein concentrations in the serum of rats treated with pharmacologic doses (5 mg/kg/d for 5 d) of the synthetic estrogen derivative ethinyl estradiol. The results show that in rats, estrogen-induced hypolipidemia is associated with a nearly complete absence of the lipid and protein moieties normally found in d less than 1.21 fraction of serum. Quantitation of specific apolipoproteins by immunoelectrophoresis show that most apolipoproteins are decreased by more than 90% in the serum of estrogen-treated rats. In contrast to the changes in d less than 1.21 lipoproteins, estrogen treatment only slightly reduced serum phospholipid concentrations (by only 10%) and caused no change in the concentration of serum albumin. The results show that the ethinyl estradiol-treated rat is an excellent model of drug-induced hypolipidemia. | lld:pubmed |
pubmed-article:708487 | pubmed:language | eng | lld:pubmed |
pubmed-article:708487 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:708487 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:708487 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:708487 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:708487 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:708487 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:708487 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:708487 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:708487 | pubmed:month | Aug | lld:pubmed |
pubmed-article:708487 | pubmed:issn | 0021-9150 | lld:pubmed |
pubmed-article:708487 | pubmed:author | pubmed-author:RoheimP SPS | lld:pubmed |
pubmed-article:708487 | pubmed:author | pubmed-author:DavisR ARA | lld:pubmed |
pubmed-article:708487 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:708487 | pubmed:volume | 30 | lld:pubmed |
pubmed-article:708487 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:708487 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:708487 | pubmed:pagination | 293-9 | lld:pubmed |
pubmed-article:708487 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:708487 | pubmed:meshHeading | pubmed-meshheading:708487-A... | lld:pubmed |
pubmed-article:708487 | pubmed:year | 1978 | lld:pubmed |
pubmed-article:708487 | pubmed:articleTitle | Pharmacologically induced hypolipidemia. The ethinyl estradiol-treated rat. | lld:pubmed |
pubmed-article:708487 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:708487 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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