| pubmed-article:7076115 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7076115 | lifeskim:mentions | umls-concept:C0005775 | lld:lifeskim |
| pubmed-article:7076115 | lifeskim:mentions | umls-concept:C0003313 | lld:lifeskim |
| pubmed-article:7076115 | lifeskim:mentions | umls-concept:C0020835 | lld:lifeskim |
| pubmed-article:7076115 | lifeskim:mentions | umls-concept:C0449297 | lld:lifeskim |
| pubmed-article:7076115 | lifeskim:mentions | umls-concept:C0205431 | lld:lifeskim |
| pubmed-article:7076115 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:7076115 | pubmed:dateCreated | 1982-7-19 | lld:pubmed |
| pubmed-article:7076115 | pubmed:abstractText | The formation and clearance of circulating IgA immune complexes from blood to bile was investigated in this study. The i.v. injection of either MOPC-315, an IgA M-component with antidinitrophenyl (DNP) specificity, or TEPC-15, an IgA M-component of a different specificity, was followed by i.v. injection of 125I-DNP10-bovine serum albumin (BSA) as the antigen. The formation and clearance of IgA immune complexes in the circulation of MOPC-315-treated, but not TEPC-15-treated animals was demonstrated by immunoprecipitation with polyacrylamide beads coated with rabbit anti-mouse IgA. IgA-125I-DNP10-BSA complexes were identified in the bile from MOPC-315-treated, but not TEPC-15-treated animals utilizing this same immunoprecipitation technique. These observations suggest that the liver or bile ducts transport IgA immune complexes from blood into bile. The clearance of 125I-DNP10-BSA from the circulation was documented by coprecipitation with rabbit anti-BSA and BSA. The clearance of this circulating antigen was slower in the MOPC-315-treated than in the TEPC-15-treated animals suggesting that under the conditions of the present experiment, circulating antigen is cleared more slowly after IgA immune complex formation. | lld:pubmed |
| pubmed-article:7076115 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7076115 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7076115 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7076115 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7076115 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7076115 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7076115 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7076115 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7076115 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7076115 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7076115 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7076115 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7076115 | pubmed:issn | 0270-9139 | lld:pubmed |
| pubmed-article:7076115 | pubmed:author | pubmed-author:WalkerW AWA | lld:pubmed |
| pubmed-article:7076115 | pubmed:author | pubmed-author:BlochK JKJ | lld:pubmed |
| pubmed-article:7076115 | pubmed:author | pubmed-author:KleinmanR ERE | lld:pubmed |
| pubmed-article:7076115 | pubmed:author | pubmed-author:HarmatzP RPR | lld:pubmed |
| pubmed-article:7076115 | pubmed:author | pubmed-author:BunnellB WBW | lld:pubmed |
| pubmed-article:7076115 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7076115 | pubmed:volume | 2 | lld:pubmed |
| pubmed-article:7076115 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7076115 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7076115 | pubmed:pagination | 328-33 | lld:pubmed |
| pubmed-article:7076115 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:meshHeading | pubmed-meshheading:7076115-... | lld:pubmed |
| pubmed-article:7076115 | pubmed:articleTitle | Hepatobiliary clearance of IgA immune complexes formed in the circulation. | lld:pubmed |
| pubmed-article:7076115 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7076115 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:7076115 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7076115 | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7076115 | lld:pubmed |
