| pubmed-article:7069344 | pubmed:abstractText | Radioimmunoassays were used for the measurement of several androgens in canine plasma and in the liquid of the vas deferens. Large variations in the plasma concentrations of androstenedione, testosterone and 5 alpha-dihydrotestosterone occurred during a period of 24 h, but there was no evidence of a circadian rhythm. The ratios of the androgen concentration in the liquid of the vas deferens compared with that in the peripheral plasma were: androstenedione, 4.6; testosterone, 1.9; 5 alpha-dihydrotestosterone, 13.6; 5 alpha-androstane-3 alpha, 17 beta-diol, 17.0; 5 alpha-diol, 22.4. These high levels of androgens in the liquid of the vas deferens could play a role in the development of prostatic hypertrophy. | lld:pubmed |
