| pubmed-article:7053244 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7053244 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:7053244 | lifeskim:mentions | umls-concept:C0027950 | lld:lifeskim |
| pubmed-article:7053244 | lifeskim:mentions | umls-concept:C0008018 | lld:lifeskim |
| pubmed-article:7053244 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:7053244 | pubmed:dateCreated | 1982-1-28 | lld:pubmed |
| pubmed-article:7053244 | pubmed:abstractText | A monoclonal IgG1 antibody, termed NCD3, was raised against human neutrophils and has been shown to inhibit neutrophil chemotaxis. NCD3 displayed a considerable degree of stimulus specificity in that it inhibited N-formyl-methionyl-leucyl-phenylalanine- (FMLP) induced chemotaxis up to 80%, C5a and zymosan-activated plasma induced chemotaxis by only 20% and had no effect on leukotriene B4- (LTB4) or casein-mediated chemotaxis. NCD3 did not inhibit granule enzyme release from neutrophils in response to stimulation by various secretagogues, including FMLP, in the presence or absence of cytochalasin B (CB). Neutrophil phagocytosis of 51Cr-labeled opsonized sheep erythrocytes (51Cr-EAC) and superoxide anion (O2-) production in response to FMLP or phorbol myristate acetate (PMA) stimulation were not affected by pretreating cells with NCD3. Divalency of NCD3 was necessary for inhibition of chemotaxis, suggesting a requirement for cross-linking of the antigenic determinants on the neutrophil membrane surface. | lld:pubmed |
| pubmed-article:7053244 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7053244 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7053244 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7053244 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:7053244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7053244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7053244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7053244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7053244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7053244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7053244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7053244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7053244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7053244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7053244 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7053244 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:7053244 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:7053244 | pubmed:author | pubmed-author:HensonP MPM | lld:pubmed |
| pubmed-article:7053244 | pubmed:author | pubmed-author:CotterT GTG | lld:pubmed |
| pubmed-article:7053244 | pubmed:author | pubmed-author:KeelingP JPJ | lld:pubmed |
| pubmed-article:7053244 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7053244 | pubmed:volume | 127 | lld:pubmed |
| pubmed-article:7053244 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7053244 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7053244 | pubmed:pagination | 2241-5 | lld:pubmed |
| pubmed-article:7053244 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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| pubmed-article:7053244 | pubmed:meshHeading | pubmed-meshheading:7053244-... | lld:pubmed |
| pubmed-article:7053244 | pubmed:year | 1981 | lld:pubmed |
| pubmed-article:7053244 | pubmed:articleTitle | A monoclonal antibody-inhibiting FMLP-induced chemotaxis of human neutrophils. | lld:pubmed |
| pubmed-article:7053244 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7053244 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7053244 | lld:pubmed |
