| pubmed-article:704358 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:704358 | lifeskim:mentions | umls-concept:C0027950 | lld:lifeskim |
| pubmed-article:704358 | lifeskim:mentions | umls-concept:C0001128 | lld:lifeskim |
| pubmed-article:704358 | lifeskim:mentions | umls-concept:C0032550 | lld:lifeskim |
| pubmed-article:704358 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:704358 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:704358 | lifeskim:mentions | umls-concept:C0871161 | lld:lifeskim |
| pubmed-article:704358 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:704358 | pubmed:dateCreated | 1978-12-20 | lld:pubmed |
| pubmed-article:704358 | pubmed:abstractText | Poly (2'-deoxy-2'-fluoroinosinic acid) [ poly(If)] was synthesized by polymerization of 2'-deoxy-2'-fluoroinosine 5'-diphosphate catalyzed by Escherichia coli polynucleotide phosphorylase. Although the UV absorption properties of poly(If) closely resembled those of poly(I), thermal melting curves at Na+ concentrations of 0.15M and 0.75M suggested two ordered structures for poly(If) neutral form. CD psectra taken at 0.15M Na+ concentration showed rather larger amplitudes in both a peak at 273 nm and a trough at 246 nm, suggesting rather strong vertical stacking of bases. When complexed with poly(C), poly(If) forms a double-stranded complex, poly(If).poly(C) which has Tm's higher by 10-20 degrees than those of poly(If).poly(C) measured under the same conditions. The CD spectrum of this complex resembled that of poly(I).poly(C). The effect of the fluorine atom at the 2'-position on thermal stability of polynucleotides is discussed. | lld:pubmed |
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| pubmed-article:704358 | pubmed:language | eng | lld:pubmed |
| pubmed-article:704358 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:704358 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:704358 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:704358 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:704358 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:704358 | pubmed:issn | 0305-1048 | lld:pubmed |
| pubmed-article:704358 | pubmed:author | pubmed-author:IkeharaMM | lld:pubmed |
| pubmed-article:704358 | pubmed:author | pubmed-author:FukuiTT | lld:pubmed |
| pubmed-article:704358 | pubmed:author | pubmed-author:KakiuchiNN | lld:pubmed |
| pubmed-article:704358 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:704358 | pubmed:volume | 5 | lld:pubmed |
| pubmed-article:704358 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:704358 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:704358 | pubmed:pagination | 3315-24 | lld:pubmed |
| pubmed-article:704358 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:704358 | pubmed:meshHeading | pubmed-meshheading:704358-P... | lld:pubmed |
| pubmed-article:704358 | pubmed:year | 1978 | lld:pubmed |
| pubmed-article:704358 | pubmed:articleTitle | Polynucleotides. LVI. Synthesis and properties of poly(2-deoxy-2'-fluoroinosinic acid). | lld:pubmed |
| pubmed-article:704358 | pubmed:publicationType | Journal Article | lld:pubmed |
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